Direct-to-Consumer Online Platforms Expand Access, but Often Fail to Convey Risks of Testosterone Therapy

Demand for testosterone therapy has soared in the United States with more men seeking to increase hormone levels in hopes of enhancing virility, strength and energy. Testosterone therapy has become a burgeoning business with direct-to-consumer men’s health platforms proliferating online in recent years. While testosterone therapy benefits some men, it can be harmful for others,...

Hormone Discovery Could Predict Long Term Health of Men

Scientists from the University of Nottingham have discovered that the novel insulin-like peptide hormone INSL3 is consistent over long periods of time and is an important early biomarker for prediction of age-linked disease and published their findings in Frontiers in Endocrinology.  Researchers led by Richard Ivell, PhD, and Ravinder Anand-Ivell, PhD, FRSB, point out that...

Stem Cells Show Promise in Treating Late-Onset Hypogonadism

Directed differentiation of human induced pluripotent (hiPSCs) into Leydig-like cells may be a novel and promising treatment for late-onset hypogonadism (LOH), according to a study recently published in Endocrinology. Researchers led by Takashi Aoi, MD, PhD, of Kobe University in Japan, point out that LOH is characterized by various symptoms, including erectile dysfunction, decreased muscle...

Is the “Love Hormone” to Blame in Men with Sex Addiction?

Men with hypersexual disorder may have higher levels of oxytocin in their blood than men without the disorder, according to a small study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism. Hypersexual disorder involves excessive, persistent sexual behaviors related to various mood states, with an impulsivity component and experienced loss of control....

No Liver Toxicity Seen in TRT Study Data Presented at ENDO 2021

The testosterone replacement therapy (TRT) testosterone undecanoate oral capsules shows no evidence of liver toxicity, according to data from a two-year, multi-center study presented at ENDO 2021. Marketed under the brand name JATENZO® by Clarus Therapeutics, Inc., this oral softgel has been commercially available since February 2020 after a March 2019 approval by the U.S....


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