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Case Study Illuminates Metreleptin’s Possible Role in Improving Lipid and Glycemic Profiles

Researchers in Japan have detailed a case report in which a young woman who survived childhood cancer was treated with metreleptin supplementation to improve her acquired incomplete lipodystrophy and published their findings in the Journal of the Endocrine Society. The researchers, led by Ayako Nagayama, MD, and Kenji Ashida, MD, PhD, (Nomura Laboratory) of Kurume...
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Protein Kinase Revealed to Regulate Body Weight and Energy Homeostasis

Researchers have identified a protein kinase that controls weight and homeostasis and when deficient or inactivated can lead to metabolic diseases like obesity and type 2 diabetes, according to a mouse study recently published in Endocrinology. Researchers led by Eiichi Hinoi of the Laboratory of Pharmacology in the Department of Bioactive Molecules at Gifu Pharmaceutical...
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Weighty Issues: The Latest in Obesity Science

Endocrine News focuses on some of the latest obesity-related endocrine research presented at ENDO 2019. From the use of a CPAP machine and the impact of excess weight on migraine headaches to the causal effects of eating late in the day and weight gain, it’s clear that obesity is a risk factor for a variety...
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Danger Ahead: New Guideline Stresses Prevention

The Endocrine Society’s latest clinical practice guideline calls for regular monitoring of key metabolic measures at routine appointments. These initial steps can alert clinicians and patients alike to any potential metabolic threats that might be lurking. Better screening to detect the metabolic risk factors for cardiovascular disease and type 2 diabetes can lead to earlier...
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Pediatric Obesity and Male Precocious Puberty: A Link Established

While the connection has been well established between obesity and precocious puberty in girls, a Chilean study presented at ENDO 2019 establishes a link between obesity and precocious puberty in boys. According to statistics from Pediatric Obesity—Assessment, Treatment, and Prevention: An Endocrine Society Clinical Practice Guideline as well as Endocrine Facts and Figures: Obesity, the...
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The Long Haul: Treating Men with Obesity with Testosterone

A study presented at ENDO 2019 shows that long-term testosterone therapy in men with obesity and hypogonadism can actually contribute to prolonged weight loss without an added risk for mortality or major cardiovascular incidents. As obesity rates around the world continue to climb – the number has tripled since 1975 – physicians and health organizations...