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Intermittent Fasting Can Help Manage Metabolic Disease

Eating daily calories within a consistent window of 8-10 hours is a powerful strategy to prevent and manage chronic diseases such as diabetes and heart disease, according to a new manuscript published in the Endocrine Society’s journal, Endocrine Reviews. Time-restricted eating is a type of intermittent fasting that limits your food intake to a certain...
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Patients Report Long-Term Favorable Effects of Weight Loss Surgery in Their Daily Lives

A new analysis from the STAMPEDE trial shows that over the course of five years, patients who had bariatric and metabolic surgery to treat uncontrolled type 2 diabetes reported greater physical health, more energy, less body pain, and less negative effects of diabetes in their daily lives, compared with patients who had medical therapy alone...
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Menopause Symptoms Have a Marked Impact on Weight Gain

After three nights of disturbed sleep, as well as after estrogen suppression with normal or disturbed sleep, women burned significantly less fat, which could explain why menopausal women have increased rates of obesity, according to a study presented in March at ENDO 2021. Leilah Grant, PhD, of Brigham and Women’s Hospital in Boston, Mass., spoke...
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Semaglutide Reduces Excess Body Fat in People with Obesity

Findings suggest drug has potential to reduce risk of heart disease, diabetes, and stroke. In adults with obesity or overweight, weekly treatment with the glucagon-like peptide 1 (GLP1) receptor agonist semaglutide leads to reduced excess body fat and increased lean body mass, according to an industry-sponsored study presented virtually at ENDO 2021. “Our findings suggest...
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Mighty Mouse: Could a Part of the Brain Unlock the Key to Combatting Obesity?

A new mouse study shows promise in addressing the ongoing worldwide obesity epidemic. By targeting a specific brain molecule, researchers could be on the path to a therapy that would potentially enable patients to reduce calories while increasing exercise levels. If Constantine A. Stratakis, MD, DSci, PhD, had his way, clinicians could soon offer their...
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Researchers Develop First-in-Class Humanized Antibody Targeting Bone and Fat

A treatment for obesity and osteoporosis could be on the horizon as Mount Sinai researchers have developed a first-in-class humanized antibody to the follicle-stimulating hormone (FSH) that will reduce body fat, increase bone mass, enhance metabolism, and lower cholesterol. The antibody has the potential to prevent and treat obesity, osteoporosis, and hypercholesterolemia — diseases that...
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Cause & Effect: Patients with Obesity and Thyroid Function Testing

According to a new guideline from the European Society of Endocrinology, patients with obesity should be routinely tested for thyroid function. However, testing for other endocrine-related conditions should be guided by the presence of symptoms. The endocrine system and obesity can have a push-pull relationship. Some endocrine disorders — such as hypothyroidism and Cushing’s syndrome...