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Study Finds Intense Exercise May Suppress Appetite in Healthy Humans

A vigorous workout does more to suppress hunger levels in healthy adults than does moderate exercise, and females may be especially susceptible to this response, according to a small study published in the Journal of the Endocrine Society. The study examines the effects of exercise intensity on ghrelin levels and appetite between men and women. Ghrelin...
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Pregnant Women Exposed to PFAS May Be at Risk for Obesity, Heart Disease Later in Life

Women with higher levels of per- and polyfluoroalkyl substances (PFAS) during pregnancy may experience long-term weight gain and heart problems later in life, according to new research published in The Journal of Clinical Endocrinology & Metabolism. PFAS are manmade chemicals found in food packaging, cookware, clothes, drinking water, personal care products and many other consumer goods. These endocrine-disrupting...
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A Relentless Pursuit: JES Invites Collaborative Obesity Research

jes_8_6cover Three editors of the Journal of the Endocrine Society (JES) recently published an editorial titled “From Fundamentals to the Clinic: Advancing Obesity Research in Endocrinology,” recognizing that the landscape of obesity research has rapidly evolved in the past five years, and that sharing scientific data is an important step toward addressing the growing global obesity...
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High Fat Diet Influences Milk Lipids in Lactating Women

Maternal exposure to a high fat diet (HFD) alters milk lipids in lactating women, enhancing adiposity and myeloid inflammation in offspring, even in early life, according to an animal study recently published in Endocrinology. Researchers led by Kanakadurga Singer, MD, and Brigid Gregg, MD, both of the University of Michigan in Ann Arbor, point out...
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Bad Reception: Unlocking a Confounding Enigma Behind Monogenic Obesity in Children

When two very different pediatric patients with obesity presented with unusually high leptin levels, endocrine researchers took notice and discovered that leptin was not adequately binding with receptors. When the young patients’ familial history was considered, solutions were finally forthcoming. About three years ago, a 19-month-old girl presented to Sidra Medicine – a women’s and...
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Bariatric Surgery Linked to Cardiovascular Improvements in People with Severe Obesity

Bariatric surgery may result in significant cardiometabolic improvements, particularly among younger, female, or white people and those without comorbidities, according to new research published in the Journal of the Endocrine Society. The United States has the highest obesity rates globally. In 2017 – 2018, about 40% of U.S. adults had obesity and 9% had severe obesity. The prevalence is...