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Teprotumumab Improves Proptosis in Thyroid Eye Disease

Teprotumumab significantly improved proptosis versus placebo in longstanding/low inflammation thyroid eye disease (TED) according to data from the first placebo-controlled trial of the drug that was recently published in The Journal of Clinical Endocrinology & Metabolism. (Horizon Therapeutics funded the trial and is marketing the drug as TEPEZZA.) Researchers led by Raymond S. Douglas, MD,...
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Standardized Testing: Universal Risk Stratification System Needed for Thyroid Nodules

With thyroid cancer patients often getting different — and sometimes conflicting — treatment recommendations from a variety of diagnostic tools, Priyanka Majety, MD, talks to Endocrine News about why it’s time for clinicians to coalesce around a single set of standards for these cases, which could potentially eliminate unnecessary procedures. Priyanka Majety, MD, assistant professor...
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Researchers Generate Functional Parathyroid Glands from Mouse Embryonic Stem Cells

Functional parathyroid glands (PTGs) can be generated from mouse embryonic stem cells (mESCs), according to a study published in Proceedings of the National Academy of Sciences (PNAS). Researchers in the Stem Cell Therapy Laboratory at Tokyo Medical and Dental University point out that treatment of hypoparathyroidism requires lifelong replacement therapy. Conventional management includes calcium supplements and...
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A Second Opinion

A novel approach to treating hypothyroidism shifts the focus from TSH levels. Rudolf Hoermann, MD, PhD, a consulting endocrinologist based in Australia, talks to Endocrine News about a new approach to treating patients with hypothyroidism. Hoermann counters that regulating the HPT axis from a T-3-inclusive perspective as well as considering other factors aside from TSH...
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Solving the Hypothyroidism Puzzle: Q&A: Antonio Bianco, MD, PhD

bianco headshot Two months after his new book, Rethinking Hypothyroidism, hit the shelves, Antonio Bianco, MD, PhD, talks to Endocrine News about, well, rethinking hypothyroidism. From his research of thyroid metabolism and deiodinases to why researchers and clinicians have often been so mystified by hypothyroidism for centuries, Bianco discusses why treating hypothyroidism is a “solution followed by...
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Pro Golfer Azahara Muñoz Shares Her Experience with Hashimoto’s Disease

Aza Photo 2 When professional golfer Azahara Muñoz started developing symptoms of Hashimoto’s thyroiditis – tiredness, cold extremities – she chalked them up to practicing too hard or traveling too much. It’s a stressful job. “You almost always have an excuse for it,” she says. But then around 2016, Muñoz noticed she began suffering from anxiety. Her hair...
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New Data Show Strong Performance of Thyroid Cancer Test in Real-World Clinical Practice

Meta-analysis presented at ENDO 2022 provides real-world evidence that a test can accurately rule out thyroid cancer in patients with indeterminate thyroid nodules and that, when the test deems a nodule as suspicious, the patient’s risk of malignancy is consistent, and higher than that reported in the test’s original clinical validation (CV) study. Veracyte is...

Endocrine News provides the latest news and research articles on thyroid conditions and treatment. For more info read this month’s issue of Endocrine News.