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Underactive Thyroid Within Normal Range May Affect Woman’s Ability to Conceive

Study suggests even mild thyroid dysfunction may contribute to unexplained infertility New research suggests that a slightly underactive thyroid may affect a women’s ability to become pregnant—even when the gland is functioning at the low end of the normal range, according to a study published in The Journal of Clinical Endocrinology & Metabolism. The study...
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Case of the Month: ESAP Special Edition

esap cover This issue highlights a special edition of ESAP, available for a limited time. Test your clinical knowledge with this free case to discover the rich intellectual legacy of endocrinology. Available on the online store. Clinical Vignette A 62-year-old man is referred for assistance in the management of hyperprolactinemia and diminished libido. Over the past 9...
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High Blood Pressure During Pregnancy Linked to Increased Risk of Offspring Obesity

When expectant mothers have elevated blood pressure during pregnancy, it may raise their children’s risk of developing childhood obesity, according to a study recently published in The Journal of Clinical Endocrinology & Metabolism. “Our study is the first to demonstrate that among pregnant women, elevated blood pressure is associated with a greater risk of overweight...
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Cabergoline Tapering Successful at Maintaining Normal Prolactin Levels in Patients with Macroprolactinomas

Tapering cabergoline (CAB) levels can still maintain normal prolactin (PRL) levels in patients with macroprolactinomas, according to a study recently published in the Journal of the Endocrine Society. Researchers led by Phillipe Chanson, MD, of Hopital de Bicetre in Le Kremlin-Bicetre, France, point out that CAB is “currently the dopamine agonist (DA) of choice” in...
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Autocrine Prolactin Associated with Endometrial Cancer Growth, Metastasis, Reduced Sensitivity to Chemotherapy

Researchers have shown that autocrine human prolactin (hPRL) promotes endometrial tumor growth and metastasis, as well as reduces sensitivity to chemotherapy, leading to worse survival outcomes. Based on this association, the investigators also point to a possible therapeutic strategy for endometrial cancer (EC). The results were published recently in Endocrinology. The team, led by Peter...