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Postmenopausal Women May Benefit from Estrogen Compound Research

Postmenopausal women have increased risk of non-alcoholic fatty liver disease due to loss of estrogen from metabolic changes. A high-fat diet further exacerbates the disease, which can progress to cirrhosis and liver failure. Hormone replacement therapy (HRT) is an effective treatment, but it carries increased risk of breast cancer, uterine cancers, and cardiovascular disease. Researchers...
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HIV-1 Establishes “Sanctuary Site” In the Testis by Disrupting Blood-Testis Barrier Function

HIV-1, the most common type of human immunodeficiency virus, invades the testis and is able to avoid combination antiretroviral (cART) drugs by permeating the blood-testis barrier (BTB) and perturbing BTB function, potentially through the Tat protein, according to a study recently published in Endocrinology. Researchers led by C. Yan Cheng, PhD, senior scientist at The...
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People with Brown Fat May Burn 15 Percent More Calories

New data highlights how cold exposure activates brown fat, energy metabolism Short-term cold exposure may help people with brown fat burn 15 percent more calories than those without, according to a small study published in The Journal of Clinical Endocrinology & Metabolism. Unlike white fat, brown fat burns calories through fatty acid oxidation and heat production and is considered a promising target in the fight against the obesity epidemic. The biggest activator of brown fat is moderate cold exposure. “This data improves our understanding of how brown fat works...