Mutations of the Fragile X messenger ribonucleoprotein 1 gene (Fmr1) — a leading genetic cause of intellectual impairment and autism — contribute to premature ovarian failure (POF) due to changes in neurons that regulate reproduction in the brain and ovaries, according to a study recently published in Frontiers in Endocrinology. Researchers led by Djurdjica Coss,...
A Determination to Succeed: The Remarkable Life and Career of Rosalyn Yalow, PhD
Rosalyn Yalow, PhD, became the first woman to serve as the Endocrine Society’s president in 1977, the same year she received the Nobel Prize for Physiology or Medicine for developing the radioimmunoassay technique for hormone measurement. Endocrine News salutes this notable “grand dame of science” with a look at her life and career, as well... Scientists from the University of Nottingham have discovered that the novel insulin-like peptide hormone INSL3 is consistent over long periods of time and is an important early biomarker for prediction of age-linked disease and published their findings in Frontiers in Endocrinology. Researchers led by Richard Ivell, PhD, and Ravinder Anand-Ivell, PhD, FRSB, point out that...
Always mystifying and bit mysterious, the pituitary is the gland that sends out the orders to the other glands in the body, from regulating the adrenals and the thyroid to coordinating reproduction. However, thanks to a worldwide collaboration and a new database, this “master gland” is slowly but surely unlocking its secrets. The pituitary –...
Excessive Smartphone Screen Time Linked to Earlier Puberty Onset
Exposure to blue light through regular use of tablets and smartphones may alter hormone levels and increase the risk of earlier puberty, according to data from a rat study presented last month at the 60th Annual European Society for Paediatric Endocrinology Meeting in Rome. Longer duration of blue light exposure was associated with earlier puberty...
Mouse Study Finds FGF21 Directs Body’s Responses to Low-Protein Diet
Reducing the amount of protein in the diet produces an array of favorable health outcomes, including an extension of lifespan, and that these effects depend on Fibroblast Growth Factor 21 (FGF21), according to a study recently published in Nature Communications. It has long been known that reducing the amount you eat improves health and extends...
When the ENDO 2022 session “Clinical Year in Review: All Things Adrenal” gets underway, Gary Hammer, MD, PhD, will treat attendees to the series of advances that have been made in adrenal science and clinical practice over the last two years, from adrenal homeostasis, glucocorticoid biology, and adrenal insufficiency to Cushing’s, tumors, pheochromocytoma, and more.... Animal study links scream sound exposure to lower egg count in female rats Female rats exposed to a scream sound may have diminished ovarian reserve and reduced fertility, according to a small animal study published in Endocrinology. Ovarian reserve is the reproductive potential left within a woman’s two ovaries based on the number and quality...
