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Newman Editor 2024

Miracle Drugs or Too Good to Be True?

Obviously, from that headline I’m referring to GLP-1s and their many similar glucagon-like peptide-1 receptor agonist cohorts that have become a medical, healthcare, and even cultural zeitgeist over the course of the last couple of years. In fact, I bet every single person reading these words can sing the Ozempic jingle right now! This month’s...
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Both Ends of the Spectrum: Talking Obesity Science with Samuel Klein, MD

The Endocrine Society’s 2026 recipient of the Outstanding Clinical Investigator Laureate Award, Samuel Klein, MD, has spent the better part of the last 30 years researching why obesity affects people differently. He talks to Endocrine News about this perplexing dilemma and how he hopes his research could one day help solve this puzzle. For more...
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Beyond the Scale: What Else Glucagon-like Peptide-1 Receptor Agonists Can Do

feb2026cover In the United States, American Heart Month is observed in February to raise awareness about cardiovascular disease, the leading cause of death worldwide. To a similar end, Endocrine News focuses on a few recent journal studies that take a closer look at the impacts of incretin-based therapies in the setting of obesity and impaired cardiovascular...
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New Research Challenges Fears of Semaglutide-Linked Thyroid Cancer Risk

The “black box” warning on the popular diabetes and weight loss drug semaglutide may be shifting from a cautionary black to a reassuring grey. A landmark study published in The Journal of Clinical Endocrinology & Metabolism reveals that semaglutide does not promote thyroid cancer; instead, it may suppress tumor growth by “reprogramming” the immune system...
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Lilly’s Oral GLP-1 Orforglipron Demonstrates Superiority in Phase 3 Diabetes Trials

Eli Lilly’s “Ozempic-in-a-pill” candidate just cleared its most significant clinical hurdle to date. The pharmaceutical giant announced that its experimental once-daily pill, orforglipron, met all primary and secondary endpoints in two pivotal Phase 3 trials: ACHIEVE-2 and ACHIEVE-5. Data indicate that this oral treatment provides superior glycemic control compared to both a standard SGLT-2 inhibitor...