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New Topline Teprotumumab-trbw Data Underscore Efficacy in Longer Disease Duration, Long-Term Durability and Potential for Retreatment in People with Thyroid Eye Disease

Two clinical trials have shown positive topline data that add to the growing body of evidence supporting the efficacy and safety of teprotumumab-trbw for the treatment of Thyroid Eye Disease (TED). Horizon Therapeutics is marketing the drug as TEPEZZA, the first medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of...
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Long-Term Culture of Human Pancreatic Slices Reveals the Regeneration of Insulin-Producing Cells in Real Time

Scientists from the Diabetes Research Institute (DRI) at the University of Miami Miller School of Medicine have developed a method allowing for the long-term culture of “pancreatic slices” to study the regeneration of the human pancreas in real time. The results, published recently in Nature Communications, demonstrate that extended cultures of near-intact human pancreatic tissue...
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COVID-19 May Pose Blood Clot Risk in Pregnant Women

New Endocrinology cover COVID-19 may increase the risk of blot cots in women who are pregnant or taking estrogen with birth control or hormone replacement therapy, according to a new manuscript published in the Endocrine Society’s journal, Endocrinology. One of the many complications of COVID-19 is the formation of blood clots in previously healthy people. Estrogen increases the chance of blood clots during pregnancy and in women taking birth control pills or hormone...
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CEU 2020 Preview: Acromegaly Update

Patients with acromegaly provide a unique challenge to endocrine clinicians. Shlomo Melmed, MB, ChB, discusses the latest breakthroughs in treating these patients which includes newly approved pharmaceuticals in his session, “Update on Acromegaly: Treatment Based on the New Guidelines.” This year, the Endocrine Society’s Clinical Endocrinology Update (CEU) will take place online as the COVID-19...
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Cinnamon May Improve Blood Sugar Control in People with Prediabetes

Cinnamon improves blood sugar control in people with prediabetes and could slow the progression to type 2 diabetes, according to a new study published in the Journal of the Endocrine Society. It is estimated that nearly 90 million people in the U.S. have prediabetes, which occurs when blood sugar levels are higher than normal and often leads to type 2 diabetes. Identifying strategies...
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Research Interrupted: Scientists Are Heeding the Call to Treat COVID-19 Patients

EN0620_cover Endocrine News spoke to two early-career researchers who were called into action to treat COVID-19 patients full time. They share their inspiring stories of how they are coping with their new duties, how their research informed their patients’ care, and what they think the future of healthcare will look like post-pandemic. Endocrine scientists routinely spend...