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Direct-to-Consumer Online Platforms Expand Access, but Often Fail to Convey Risks of Testosterone Therapy

Demand for testosterone therapy has soared in the United States with more men seeking to increase hormone levels in hopes of enhancing virility, strength and energy. Testosterone therapy has become a burgeoning business with direct-to-consumer men’s health platforms proliferating online in recent years. While testosterone therapy benefits some men, it can be harmful for others,...
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Fertility in Transgender Men: What Do We Know?

In transgender men, what are the consequences of gender-affirming hormonal therapy on fertility? Led by Molly B.  Moravek, MD, MPH, a team of researchers from the Center for Reproductive Medicine, in Ann Arbor, Mich., set out to answer that question as well as summarize the current literature on the topic of transgender men desiring reproduction...
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Case Study Illuminates Metreleptin’s Possible Role in Improving Lipid and Glycemic Profiles

Researchers in Japan have detailed a case report in which a young woman who survived childhood cancer was treated with metreleptin supplementation to improve her acquired incomplete lipodystrophy and published their findings in the Journal of the Endocrine Society. The researchers, led by Ayako Nagayama, MD, and Kenji Ashida, MD, PhD, (Nomura Laboratory) of Kurume...
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Targeting Patients with Pellets: A Look at Biodentical Hormones

Promoted to treat vague symptoms and conditions like “hormone imbalance,” custom-compounded bioidentical hormones are increasing in popularity — and problems. By the time the patient came into the care of endocrinologist Margaret Wierman, MD, she had already had her ovaries removed. She had presented to the obstetrics and gynecology department with very high testosterone levels...