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Liraglutide Increases Insulin Sensitivity Independent of Weight Loss, Study Shows

Liraglutide, the glucagon-like peptide-1 receptor (GLP-1R) agonist used to treat type 2 diabetes and obesity, can lead to rapid improvement in insulin sensitivity, according to a study recently published in Diabetes. “We know that GLP-1R agonists promote weight loss, but we were surprised to find that the GLP-1R agonist liraglutide also has rapid effects on...
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Researchers Observe Beta-Arrestin’s Mechanism in GPCRs

Beta-arrestins attach themselves to outer cell membranes, waiting for hormones or neurotransmitters to land on receptors – an unexpected and surprising finding recently published in Cell. Researchers led by Davide Calebiro, MD, professor of Molecular Endocrinology in the Institute of Metabolism and Systems Research at the University of Birmingham and Co-Director of the Centre of...
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Phthalate Exposure May Increase Diabetes Risk in Women

Endocrine-disrupting chemicals (EDCs) in plastics may contribute to diabetes risk in women, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism. Phthalates are chemicals widely used in plastics such as personal care products, children’s toys, and food and beverage packaging. Phthalate exposure is associated with reduced fertility, diabetes and other endocrine disorders....

Diabetes Research Articles

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