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Vascular Endothelial Growth Factor May Prevent Defective Uterine Artery Remodeling

Vascular endothelial growth factor (VEGF) delivery selectively to the placental basal plate (PBM) may prevent maternal and neonatal impairments caused by defective uterine artery remodeling (UAR), according to a primate study recently accepted for publication in Endocrinology. Researchers led by Eugene Albrecht, PhD, a professor of medicine in the Department of Obstetrics, Gynecology, and Reproductive...
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Statins Linked to Higher Diabetes Risk

Individuals who take statins may be at higher risk for developing high blood sugar levels, insulin resistance, and eventually type 2 diabetes, according to an analysis published in the British Journal of Clinical Pharmacology. Researchers led by Prof. Bruno Stricker, of the Erasmus Medical Centre, in the Netherlands point out that while there are several epidemiological...
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Genetic Studies Provide Possible Mechanistic Link Between Endometriosis and Ovarian Cancer

Genetic breakthroughs from three recent whole-exome sequencing studies of endometrial and endometriotic epithelial cells provided some unexpected findings linking endometriosis and ovarian cancer, according to a paper recently published in Endocrinology. The paper, by Serdar E. Bulun, MD, of the Feinberg School of Medicine at Northwestern University in Chicago, notes that while associations between endometriosis...
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Researchers Reveal Novel Mechanism in Luminal Breast Cancer Development

Researchers have identified unique isoform-specific functions of phosphorylated progesterone receptors (PRs) as pathway drivers in the development of luminal breast cancer, according to a study recently published in Endocrinology. Researchers led by Carol A. Lange, PhD, of the Masonic Cancer Center at the University of Minnesota in Minneapolis, point out that luminal, or estrogen receptor...