People with elevated levels of insulin also have defects in an enzyme important to the processing of a key fatty acid from the diet, according to research recently published in Cell Metabolism. The study may help explain how excess weight can contribute to diabetes and may provide researchers with a target to help prevent or...
When professional golfer Azahara Muñoz started developing symptoms of Hashimoto’s thyroiditis – tiredness, cold extremities – she chalked them up to practicing too hard or traveling too much. It’s a stressful job. “You almost always have an excuse for it,” she says. But then around 2016, Muñoz noticed she began suffering from anxiety. Her hair...
A higher prevalence of the evening chronotype in women with polycystic ovary syndrome (PCOS) is associated with a worse hormonal and metabolic profile, according to a paper recently published in the Journal of Pineal Research. Researchers led by Giovanna Muscogiuri, MD, PhD, an assistant professor in the Unit of Endocrinology at Federico II University Medical...
Exposure to blue light through regular use of tablets and smartphones may alter hormone levels and increase the risk of earlier puberty, according to data from a rat study presented last month at the 60th Annual European Society for Paediatric Endocrinology Meeting in Rome. Longer duration of blue light exposure was associated with earlier puberty...
A study presented at ENDO 2022 in Atlanta this past summer suggests that active testosterone therapy for transgender men may negatively impact IVF outcomes. Research presented by Amanda Schwartz, MD, a reproductive endocrinology and infertility fellow at the University of Michigan, found that female mice currently receiving testosterone had fewer and less developed eggs retrieved....
Women who are longer-term survivors of metastatic breast cancer may have a worse survival rate if they have diabetes and poorly controlled blood sugar levels, according to a study presented at ENDO 2022. The authors of the study point out that a well-established relationship between diabetes and breast cancer exists, but it’s still unclear how...
Researchers from the University of Basel and University Hospital Basel have identified how the sensory perception of a meal generates a signal to the pancreas to ramp up insulin production: inflammatory factor interleukin 1 beta (IL1β), which is also involved in the immune response to pathogens or in tissue damage. The team reported their findings...
ENDO 2022 saw the presentation of positive clinical data from the open-label extensions (OLEs) of two of the Phase 3 trials of oral octreotide for patients with acromegaly. Amryt is marketing the drug as Mycapssa. Data presented in a late-breaking poster presentation of the 2nd year of the OLE of OPTIMAL (NCT03252353), a randomized, double-blind...