Researchers have described clinical features and outcomes in children with adrenocortical tumors (ACTs) without germline TP53 mutations, according to a study recently published in the Journal of Clinical Oncology. Emilia Modolo Pinto, PhD, Raul C. Ribeiro, MD, and colleagues of St. Jude Children’s Research Hospital in Memphis, Tenn., point out that ACTs are cancers caused...
Researchers have shown that somatic USP8 gene mutations are a common cause of pediatric Cushing disease (CD), according to a study recently published in The Journal of Clinical Endocrinology & Metabolism. The team, led by Constantine A. Stratakis, MD, of the National Institutes of Health in Bethesda, Md., point out that this mutation has been...
An Ounce of Prevention: New Studies Look at Childhood Obesity