Therapeutic program targets a novel mechanism of melatonin receptor action outside of the CNS Celmatix Inc. today announced its latest drug program that targets melatonin receptors outside of the central nervous system (CNS). The company hopes the therapeutic drug will address a critical gap in the market for effective first-line treatments for a range of...
Paraben Exposure Linked to Mammary Cancer Growth and Metastasis
Parabens like methylparaben (MP) and propylparaben (PP), which are commonly used in food, cosmetic, and drug preservatives, are associated with mammary cancer growth and metastasis in mice, according to a study recently published in Endocrinology. Researchers led by Michele A. La Merrill, PhD, of the Department of Environmental Toxicology at the University of California at...
Demand for testosterone therapy has soared in the United States with more men seeking to increase hormone levels in hopes of enhancing virility, strength and energy. Testosterone therapy has become a burgeoning business with direct-to-consumer men’s health platforms proliferating online in recent years. While testosterone therapy benefits some men, it can be harmful for others,...
Honored by both the Endocrine Society and the European Society of Endocrinology with the 2023 Transatlantic Alliance Award, George Chrousos, MD, ScD, has made significant contributions to endocrine research on both sides of the Atlantic! Endocrine News speaks with Chrousos about what this award means to him, conducting pioneering research on two different continents, the...
Higher Prevalence of Evening Chronotype in Women with PCOS Associated with Worse Metabolic Profile
A higher prevalence of the evening chronotype in women with polycystic ovary syndrome (PCOS) is associated with a worse hormonal and metabolic profile, according to a paper recently published in the Journal of Pineal Research. Researchers led by Giovanna Muscogiuri, MD, PhD, an assistant professor in the Unit of Endocrinology at Federico II University Medical...
Scientists from the University of Nottingham have discovered that the novel insulin-like peptide hormone INSL3 is consistent over long periods of time and is an important early biomarker for prediction of age-linked disease and published their findings in Frontiers in Endocrinology. Researchers led by Richard Ivell, PhD, and Ravinder Anand-Ivell, PhD, FRSB, point out that...
Cryos International Sperm and Egg Bank recently announced a published scientific study which suggests that the use of Virtual Reality (VR) headsets during sperm donation has a positive effect on sperm quality. The study can be viewed in Reproductive Biology and Endocrinology. During the summer of 2021 Cryos International introduced VR headsets in the donor...
Rebound Weight Gain in Children with Obesity Linked to Disconnect between Brain and Gut
Children with obesity who have recently lost weight are more likely to show hunger-related activity in their brains after a meal, according to research presented at the 60th Annual European Society for Paediatric Endocrinology Meeting. This brain activity, reflecting that they were unsatisfied by their meal, happens even though their gut hormone levels have changed, as...