Researchers have described clinical features and outcomes in children with adrenocortical tumors (ACTs) without germline TP53 mutations, according to a study recently published in the Journal of Clinical Oncology. Emilia Modolo Pinto, PhD, Raul C. Ribeiro, MD, and colleagues of St. Jude Children’s Research Hospital in Memphis, Tenn., point out that ACTs are cancers caused...
This issue highlights a special edition of ESAP, available for a limited time. Test your clinical knowledge with this free case to discover the rich intellectual legacy of endocrinology. Available on the online store. Clinical Vignette A 62-year-old man is referred for assistance in the management of hyperprolactinemia and diminished libido. Over the past 9...
A Practical Approach to Using Trend Arrows on the Dexcom G5 CGM System for the Management of Adults With Diabetes A Practical Approach to Using Trend Arrows on the Dexcom G5 CGM System to Manage Children and Adolescents With Diabetes After the FDA approved the Dexcom G5 Mobile CGM for use in treatment decisions, the...Review Looks at Implications of Free Testosterone Measurements
The number of testosterone prescriptions is growing, so a paper recently published in Endocrine Reviews seeks to offer some best practices for the application of free testosterone measurements in patients with androgen disorders. The paper, by Ravi Jasuja, PhD, of Harvard Medical School, et al, points out that as the number of prescriptions written for...
This issue highlights Pediatric Endocrine Self-Assessment Program. Test your clinical knowledge and prepare for your exam. Available on the online store. Clinical Vignette You are called by the neonatal intensive care unit to consult on a newborn girl with fractures. The baby’s parents state concerns were initially raised after a 20-week prenatal ultrasound showed... Study finds higher risk and earlier diagnosis of diabetes in women with PCOS Women who have polycystic ovary syndrome (PCOS) have a higher risk of developing type 2 diabetes (T2D) and are diagnosed at an earlier age with the condition, according to a new study published in The Journal of Clinical Endocrinology & Metabolism. The...
Researchers have shown that somatic USP8 gene mutations are a common cause of pediatric Cushing disease (CD), according to a study recently published in The Journal of Clinical Endocrinology & Metabolism. The team, led by Constantine A. Stratakis, MD, of the National Institutes of Health in Bethesda, Md., point out that this mutation has been...
New Recommendations for Managing Menopausal Symptoms in Breast Cancer Survivors
Review highlights individualized non-hormonal therapies for symptom treatment A large proportion of the world’s estimated 9.3 million breast cancer survivors experience menopausal symptoms or clinical manifestations of estrogen deficiency. A comprehensive review published in The Journal of Clinical Endocrinology & Metabolism focuses on current and future approaches to management of menopausal symptoms after breast cancer. Menopause...
