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Primary Care: Pediatricians Urge Greater Access to Surgery for Severely Obese Youth

As childhood obesity becomes an “epidemic within an epidemic,” new guidance from the American Academy of Pediatrics echoes Endocrine Society recommendations on bariatric surgery for severely obese young people. Aside from reducing their weight, these procedures could benefit young people well into adulthood. Improved access to bariatric surgery is “urgently needed” for the severely obese...
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Mild Thyroid Dysfunction Affects One in Five Women with a History of Miscarriage or Subfertility

Mild thyroid abnormalities affect up to one in five women with a history of miscarriage or subfertility which is a prolonged time span of trying to become pregnant, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism. Thyroid disorders are common in women of reproductive age. Although the prevalence of thyroid disorders in pregnancy are well understood,...
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Fair Trials: The Need for Representation in Clinical Trials

JRG_2018-photo One of the biggest obstacles to medical research is the lack of a truly representative population in clinical trials. For his ENDO Online 2020 session, “Minority Participation in Research: Considerations of Urgency and Strategy,” James R. Gavin III, MD, PhD, will discuss needed steps researchers can take to ensure clinical trials are representative of all...
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New Report on Estradiol Ranges in Postmenopausal Women Released

Updated recommendations to establish normal estradiol reference ranges have been released in a new report from the North American Menopause Society (NAMS). The report is based on a symposium called “Workshop on Normal Reference Ranges for Estradiol in Postmenopausal Women,” that was held in September 2019, in Chicago, Ill., and featured 28 presentations. The Endocrine...
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Study Finds PFAS Exposure May Cause Early Menopause

Per- and polyfluoroalkyl substance (PFAS) exposure may cause menopause to occur two years earlier in women, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism. Known as ‘forever chemicals,’ PFAS are manmade and used in a wide variety of nonstick and waterproof products and firefighting foams. PFAS chemicals can contaminate drinking water, and it has been estimated that 110 million Americans (one out of three) may consume drinking water contaminated with these chemicals. “PFAS are everywhere....
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Fertility in Transgender Men: What Do We Know?

In transgender men, what are the consequences of gender-affirming hormonal therapy on fertility? Led by Molly B.  Moravek, MD, MPH, a team of researchers from the Center for Reproductive Medicine, in Ann Arbor, Mich., set out to answer that question as well as summarize the current literature on the topic of transgender men desiring reproduction...
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Insulin Sensitivity Improves with Testosterone Therapy in Men with Type 2 Diabetes and Hypogonadism

About a third of men with type 2 diabetes (T2D) also have hypogonadotropic hypogonadism (HH). This comorbidity makes that subgroup more insulin resistant, with increased adiposity and less lean mass, according to research published recently in The Journal of Clinical Endocrinology & Metabolism. A team led by Paresh Dandona, BSc, MB, BS, DPhil, FRCP, of...