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Mild thyroid abnormalities affect up to one in five women with a history of miscarriage or subfertility which is a prolonged time span of trying to become pregnant, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism. Thyroid disorders are common in women of reproductive age. Although the prevalence of thyroid disorders in pregnancy are well understood,...
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One of the biggest obstacles to medical research is the lack of a truly representative population in clinical trials. For his ENDO Online 2020 session, “Minority Participation in Research: Considerations of Urgency and Strategy,” James R. Gavin III, MD, PhD, will discuss needed steps researchers can take to ensure clinical trials are representative of all...
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Updated recommendations to establish normal estradiol reference ranges have been released in a new report from the North American Menopause Society (NAMS). The report is based on a symposium called “Workshop on Normal Reference Ranges for Estradiol in Postmenopausal Women,” that was held in September 2019, in Chicago, Ill., and featured 28 presentations. The Endocrine...
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Per- and polyfluoroalkyl substance (PFAS) exposure may cause menopause to occur two years earlier in women, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism. Known as ‘forever chemicals,’ PFAS are manmade and used in a wide variety of nonstick and waterproof products and firefighting foams. PFAS chemicals can contaminate drinking water, and it has been estimated that 110 million Americans (one out of three) may consume drinking water contaminated with these chemicals. “PFAS are everywhere....
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In transgender men, what are the consequences of gender-affirming hormonal therapy on fertility? Led by Molly B. Moravek, MD, MPH, a team of researchers from the Center for Reproductive Medicine, in Ann Arbor, Mich., set out to answer that question as well as summarize the current literature on the topic of transgender men desiring reproduction...
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About a third of men with type 2 diabetes (T2D) also have hypogonadotropic hypogonadism (HH). This comorbidity makes that subgroup more insulin resistant, with increased adiposity and less lean mass, according to research published recently in The Journal of Clinical Endocrinology & Metabolism. A team led by Paresh Dandona, BSc, MB, BS, DPhil, FRCP, of...
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As men age, testosterone levels decrease, but current guidelines recommend testing in symptomatic men only, and there has been a lack of consensus about what point that decrease becomes a deficiency. Healthy aging men have been presumed to have higher serum testosterone levels than their counterparts with obesity, smoking history, or associated comorbidities, but large-scale...
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Testosterone supplementation prevents an increase in circulating ghrelin but does not appear to affect appetite or energy intake in healthy men who are suffering from a severe, short-term energy deficit, according to a study recently published in the Journal of the Endocrine Society. Researchers led by J. Philip Karl, PhD, RD, and Stefan M. Pasiakos,...
