Share

Long-Term Diabetes Complication: Liver Inflammation Raises Cholesterol Levels

Inflammatory processes in the liver lead to elevated cholesterol levels in people with diabetes, thus promoting subsequent vascular diseases, according to a study by researchers at Helmholtz Zentrum München, Technische Universität München (TUM) and the Collaborative Research Center SFB 1118 at Heidelberg University Hospital. The paper was recently published in Cell Reports. “Even if blood...
Share

Machine-Learning Techniques Unlock Hidden Benefit of Weight Loss Interventions for Overweight Patients with Type 2 Diabetes

Losing weight reduces the risk of long-term cardiovascular illness and mortality for the majority of patients with type 2 diabetes, but for a small subgroup, weight-loss intervention can lead to dramatically worse outcomes, according a study published recently in The Lancet Diabetes & Endocrinology. Researchers led by James H. Faghmous, PhD, chief technology officer at...
Share

Type 1 Diabetes Organ Donors Show High Rates of Illicit Drug Use and Suicide

A letter published recently in Diabetes Care says that there is a high rate of illicit drug use and suicide in people with type 1 diabetes who donate their pancreases to the Network of Pancreatic Organ Donors with Diabetes (nPOD). This network collects, processes, and distributes these organs to researchers studying diabetes around the world....
Share

Short, High-Intensity Exercise Sessions Improve Insulin Production in Type 2 Diabetes

Short, functional-movement and resistance training workouts, called functional high-intensity training (F-HIT) may improve beta-cell function in adults with type 2 diabetes, according to a study recently published in the American Journal of Physiology—Endocrinology and Metabolism. Researchers led by John P. Kirwan, PhD, of Cleveland Clinic, point out that previous research has shown that aerobic exercise...
Share

Cabergoline Tapering Successful at Maintaining Normal Prolactin Levels in Patients with Macroprolactinomas

Tapering cabergoline (CAB) levels can still maintain normal prolactin (PRL) levels in patients with macroprolactinomas, according to a study recently published in the Journal of the Endocrine Society. Researchers led by Phillipe Chanson, MD, of Hopital de Bicetre in Le Kremlin-Bicetre, France, point out that CAB is “currently the dopamine agonist (DA) of choice” in...
Share

Autocrine Prolactin Associated with Endometrial Cancer Growth, Metastasis, Reduced Sensitivity to Chemotherapy

Researchers have shown that autocrine human prolactin (hPRL) promotes endometrial tumor growth and metastasis, as well as reduces sensitivity to chemotherapy, leading to worse survival outcomes. Based on this association, the investigators also point to a possible therapeutic strategy for endometrial cancer (EC). The results were published recently in Endocrinology. The team, led by Peter...
Share

Researchers Studying Novel Gestational Diabetes Screening Alternative

Researchers at Brigham and Women’s Hospital (BWH) recently published a study demonstrating the potential clinical utility of glycated CD59 (GCD59) as a novel biomarker for the screening and diagnosis of gestational diabetes mellitus (GDM). The data from this study showed that a single blood test that measures plasma GCD59 at week 24-28 of gestation identified...
Share

Personalized Insulin Dosing Could Lead to Better Outcomes Following CABG Surgery

A study from Emory University published in the April 2017 issue of Journal of Diabetes and Its Complications observes a near-20% reduction in perioperative complications, a 1.2-day reduction in ICU stay, and a $3,654 reduction in per-patient hospitalization costs for coronary artery bypass graft (CABG) surgery. The reported outcomes, which included no severe hypoglycemia less...