Share

Cabergoline Tapering Successful at Maintaining Normal Prolactin Levels in Patients with Macroprolactinomas

Tapering cabergoline (CAB) levels can still maintain normal prolactin (PRL) levels in patients with macroprolactinomas, according to a study recently published in the Journal of the Endocrine Society. Researchers led by Phillipe Chanson, MD, of Hopital de Bicetre in Le Kremlin-Bicetre, France, point out that CAB is “currently the dopamine agonist (DA) of choice” in...
Share

Autocrine Prolactin Associated with Endometrial Cancer Growth, Metastasis, Reduced Sensitivity to Chemotherapy

Researchers have shown that autocrine human prolactin (hPRL) promotes endometrial tumor growth and metastasis, as well as reduces sensitivity to chemotherapy, leading to worse survival outcomes. Based on this association, the investigators also point to a possible therapeutic strategy for endometrial cancer (EC). The results were published recently in Endocrinology. The team, led by Peter...
Share

Researchers Studying Novel Gestational Diabetes Screening Alternative

Researchers at Brigham and Women’s Hospital (BWH) recently published a study demonstrating the potential clinical utility of glycated CD59 (GCD59) as a novel biomarker for the screening and diagnosis of gestational diabetes mellitus (GDM). The data from this study showed that a single blood test that measures plasma GCD59 at week 24-28 of gestation identified...
Share

Personalized Insulin Dosing Could Lead to Better Outcomes Following CABG Surgery

A study from Emory University published in the April 2017 issue of Journal of Diabetes and Its Complications observes a near-20% reduction in perioperative complications, a 1.2-day reduction in ICU stay, and a $3,654 reduction in per-patient hospitalization costs for coronary artery bypass graft (CABG) surgery. The reported outcomes, which included no severe hypoglycemia less...
Share

Low Body Mass Index Not Associated with Alzheimer’s Disease

Low body mass index is not associated with an increased risk of Alzheimer’s disease after all, according to a recent study published in The Journal of Clinical Endocrinology & Metabolism. Researchers led by Ruth Frikke-Schmidt, MD, DMSc, PhD, chief physician at Rigshospitalet in Copenhagen, Denmark, and associate research professor at the University of Copenhagen, point...
Share

Can Intensive Medical Treatment Reverse Type 2 Diabetes?

Type 2 diabetes can be reversed with intensive medical treatment using oral medications, insulin and lifestyle therapies, according to a study published in The Journal of Clinical Endocrinology & Metabolism. Researchers led by Hertzel C. Gerstein, MD, MSc, FRCPC, of McMaster University and Hamilton Health Sciences in Hamilton, Ontario, Canada randomly divided 83 individuals with...