In yet another indictment of endocrine-disrupting chemicals, researchers have found a mechanism through which tributyltin (TBT) causes obesity and alters adipose lineage, according to an article recently published in Endocrinology. The researchers, led by Bruce Blumberg, PhD, of the University of California, Irvine, point out that nearly 40 percent of American adults are now obese,...
The number of testosterone prescriptions is growing, so a paper recently published in Endocrine Reviews seeks to offer some best practices for the application of free testosterone measurements in patients with androgen disorders. The paper, by Ravi Jasuja, PhD, of Harvard Medical School, et al, points out that as the number of prescriptions written for...
Researchers have found that elderly onset type 2 diabetes (eT2DM) is distinct from middle-age-onset type 2 diabetes (mT2DM), according to a study published recently in The Journal of Clinical Endocrinology & Metabolism. The investigators, led by Hiroki Mizukami, MD, PhD, of the Hirosaki University Graduate School of Medicine, in Hirosaki, Japan, point out that as...
A paper published recently in the Journal of the Endocrine Society details a case of a woman with acromegaly-like features, but she did not have excess growth hormone (GH) secretion. The authors use the case to show that differential diagnoses should be considered in these patients with “pseudoacromegaly” or “acromegaloidism.” The paper, by Per Dahlqvist,...
A paper recently published in Endocrine Reviews is addressing the controversies that exist in managing low-risk differentiated thyroid cancer (DTC), since these controversies expose patients to the risk of being over- or undertreated. The review, by Megan R. Haymart, MD, of the University of Michigan, et al, points out that the controversies extend across all...
Researchers have shown that somatic USP8 gene mutations are a common cause of pediatric Cushing disease (CD), according to a study recently published in The Journal of Clinical Endocrinology & Metabolism. The team, led by Constantine A. Stratakis, MD, of the National Institutes of Health in Bethesda, Md., point out that this mutation has been...
Inflammatory processes in the liver lead to elevated cholesterol levels in people with diabetes, thus promoting subsequent vascular diseases, according to a study by researchers at Helmholtz Zentrum München, Technische Universität München (TUM) and the Collaborative Research Center SFB 1118 at Heidelberg University Hospital. The paper was recently published in Cell Reports. “Even if blood...
Losing weight reduces the risk of long-term cardiovascular illness and mortality for the majority of patients with type 2 diabetes, but for a small subgroup, weight-loss intervention can lead to dramatically worse outcomes, according a study published recently in The Lancet Diabetes & Endocrinology. Researchers led by James H. Faghmous, PhD, chief technology officer at...
A paper published recently in the Journal of the Endocrine Society details a case of a woman with acromegaly-like features, but she did not have excess growth hormone (GH) secretion. The authors use the case to show that differential diagnoses should be considered in these patients with “pseudoacromegaly” or “acromegaloidism.” The paper, by Per Dahlqvist,...
