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How Cancer Affects Childhood Growth

Childhood cancer patients and survivors are at increased risk for growth disturbances, for myriad reasons, and it is important to periodically monitor their growth, according to a paper recently published in The Journal of Clinical Endocrinology & Metabolism. Tomoko Yoshida, MD, PhD, and Angela Delaney, MD, both of St. Jude Children’s Research Hospital in Memphis,...
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Increase in Pappalysin Levels Could Promote IGF-1 Bioavailability in Children with Prader-Willi Syndrome

The increase in free insulin-like growth factor (IGF)-I levels in prepubertal children with Prader-Willi Syndrome (PWS) treated with exogenous growth hormone (GH) could be caused by increased pregnancy-associated plasma protein A (PAPP-A, PAPP-A2) levels and a reduction in stanniocalcins (STC-1, STC-2), according to a study recently published in The Journal of Clinical Endocrinology & Metabolism....
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Children Who Are Sedentary May Have a Higher Risk of Heart Attack or Stroke Later in Life

Children who are physically inactive may have high cholesterol in early adulthood and subsequent heart health issues in their mid-forties, according to new research published in The Journal of Clinical Endocrinology & Metabolism. High cholesterol during childhood has been associated with early signs of heart disease when individuals reach their mid-twenties and an increased risk of...
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Making a Statement

Released in May, “Endocrine Health and Health Care Disparities in the Pediatric and Sexual and Gender Minority Populations: An Endocrine Society Scientific Statement,” was a featured session on the last day of ENDO 2023. Endocrine News spoke to some of the authors about these updated treatment protocols. Year after year, the Endocrine Society’s Annual Conferences...
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Self-Esteem of Children with Short Stature Tied to Social Supports, Not Height

In otherwise healthy short children, quality of life and self-esteem are associated with coping skills and how supported they feel, not the degree of their short stature, according to a study recently published in The Journal of Pediatrics. Researchers led by Adda Grimberg, MD, a pediatric endocrinologist and Scientific Director of the Growth Center at Children’s...
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Such Great Heights

ENDO_2023_4C Pediatric growth hormone deficiency treatments could soon be painless. Fernando Cassorla, MD, is traveling from Chile to Chicago to present research at ENDO 2023 that could potentially change the way pediatric hormone treatments are administered. If a pill could replace painful injections, patients and caregivers alike can finally wipe away their tears. A convenient, well...
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FDA Approves Once-Weekly Sogroya® for the Treatment of Children Living with Growth Hormone Deficiency

The U.S. Food and Drug Administration (FDA) last month approved a new indication for somapacitan-beco injection 5 mg, 10 mg, or 15 mg for the treatment of children aged 2.5 years and older who have growth failure due to inadequate secretion of endogenous growth hormone. Novo Nordisk is marketing the treatment as Sogroya® The FDA approval...