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Mouse Study Hints at Specific Brain Receptor behind PCOS Symptoms

Deletion of androgen receptors (ARs) in leptin receptor (LepRb) neurons improves estrous cycles, providing a possible therapeutic target for the symptoms of polycystic ovarian syndrome (PCOS), according to a mouse study recently published in Endocrinology. Researchers led by Carol F. Elias, PhD, of the University of Michigan Medical School’s Department of Molecular and Integrative Physiology,...
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Such Great Heights

ENDO_2023_4C Pediatric growth hormone deficiency treatments could soon be painless. Fernando Cassorla, MD, is traveling from Chile to Chicago to present research at ENDO 2023 that could potentially change the way pediatric hormone treatments are administered. If a pill could replace painful injections, patients and caregivers alike can finally wipe away their tears. A convenient, well...
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Endocrine Society’s New Scientific Statement Identifies Research Gaps in Pediatric, LGBTQIA Care

In a new Scientific Statement released today, the Endocrine Society identifies areas for future endocrine research to reduce health disparities in pediatric and sexual and gender minoritized populations.  This Scientific Statement expands the Society’s 2012 statement by focusing on endocrine disease disparities in the pediatric and sexual and gender minoritized populations. These include pediatric and...
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FDA Approves Once-Weekly Sogroya® for the Treatment of Children Living with Growth Hormone Deficiency

The U.S. Food and Drug Administration (FDA) last month approved a new indication for somapacitan-beco injection 5 mg, 10 mg, or 15 mg for the treatment of children aged 2.5 years and older who have growth failure due to inadequate secretion of endogenous growth hormone. Novo Nordisk is marketing the treatment as Sogroya® The FDA approval...
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Paraben Exposure Linked to Mammary Cancer Growth and Metastasis

Parabens like methylparaben (MP) and propylparaben (PP), which are commonly used in food, cosmetic, and drug preservatives, are associated with mammary cancer growth and metastasis in mice, according to a study recently published in Endocrinology. Researchers led by Michele A. La Merrill, PhD, of the Department of Environmental Toxicology at the University of California at...
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Direct-to-Consumer Online Platforms Expand Access, but Often Fail to Convey Risks of Testosterone Therapy

Demand for testosterone therapy has soared in the United States with more men seeking to increase hormone levels in hopes of enhancing virility, strength and energy. Testosterone therapy has become a burgeoning business with direct-to-consumer men’s health platforms proliferating online in recent years. While testosterone therapy benefits some men, it can be harmful for others,...
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The “Congenital” Scientist

EN_01_2023_US_FINALCOVER Honored by both the Endocrine Society and the European Society of Endocrinology with the 2023 Transatlantic Alliance Award, George Chrousos, MD, ScD, has made significant contributions to endocrine research on both sides of the Atlantic! Endocrine News speaks with Chrousos about what this award means to him, conducting pioneering research on two different continents, the...