Q&A with JoAnn Manson, MD, DrPH, MACP Endocrine News talks to the Endocrine Society’s 2025 Outstanding Clinical Investigator Laureate JoAnn Manson, MD, DrPH, MACP, about her ongoing research on menopausal estrogen therapy, the risks and benefits of nutritional supplements, her numerous large-scale prevention trials, and why she feels that the concept of a “healthspan” is...
Males diagnosed with classic congenital hyperplasia (CAH) due to 21-hydroxylase deficiency require lifelong treatment, with adolescence the most challenging treatment period, notes a review article in The Journal of Clinical Endocrinology & Metabolism and a supplement sponsored by Neurocrine Biosciences, Inc., an American biopharmaceutical company that develops for neurological and endocrine-related disorders. To replace the...
An Endocrine News roundup of the week’s pharmaceutical news, breakthroughs, and general information. * Positive Long-Term Results from Phase 2 HELIOS Clinical Trial of AMX0035 in People with Wolfram Syndrome On May 12, Amylyx Pharmaceuticals, Inc. announced positive Week 48 data from the Phase 2 open-label HELIOS clinical trial of AMX0035 (sodium phenylbutyrate [PB] and...
Three Studies Reveal New Insights into Osteoporosis and Bone Health A trio of studies from the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism examines several issues relating to bone health complications. These papers looked at treatment options to increase bone density in breast cancer patients; the impact of sleeve gastrectomy procedures on bone mass...
An Endocrine News roundup of the week’s pharmaceutical news, breakthroughs, and general information. * New OTC Weight Loss Pill Granted Patent On May 6, Olfactive Biosolutions was granted a patent for formulations of food molecules that cause significant weight loss when taken as a daily pill. The company’s Pivit supplement induces the simultaneous secretion of...
What goes on in the womb does not stay in the womb as prenatal hormone exposure plays a critical role in shaping childhood growth and body composition. A recent study published in The Journal of Clinical Endocrinology & Metabolism suggests that prenatal testosterone exposure is linked to sex-specific body composition changes, with boys exposed to...
A new study in The Journal of Clinical Endocrinology & Metabolism has revealed that Black/African Americans are significantly more likely to develop severe insulin-deficient diabetes (SIDD), a more serious form of the disease, compared to White Americans. Using data-driven cluster analysis, a technique widely used within the field of artificial intelligence (AI) and Machine Learning,...
A new study has found that bone marrow fat content, as measured by advanced imaging techniques, does not predict the risk of fractures in postmenopausal women. The findings, recently published in The Journal of the Endocrine Society, challenge the idea that bone marrow adipose tissue (BMAT) plays a significant role in fracture susceptibility and suggest...
Males diagnosed with classic congenital hyperplasia (CAH) due to 21-hydroxylase deficiency require lifelong treatment, with adolescence the most challenging treatment period, notes a review article in The Journal of Clinical Endocrinology & Metabolism and a supplement sponsored by Neurocrine Biosciences, Inc., an American biopharmaceutical company that develops for neurological and endocrine-related disorders. To replace the...
