Per- and polyfluoroalkyl substance (PFAS) exposure may cause menopause to occur two years earlier in women, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism. Known as ‘forever chemicals,’ PFAS are manmade and used in a wide variety of nonstick and waterproof products and firefighting foams. PFAS chemicals can contaminate drinking water, and it has been estimated that 110 million Americans (one out of three) may consume drinking water contaminated with these chemicals. “PFAS are everywhere....
In transgender men, what are the consequences of gender-affirming hormonal therapy on fertility? Led by Molly B. Moravek, MD, MPH, a team of researchers from the Center for Reproductive Medicine, in Ann Arbor, Mich., set out to answer that question as well as summarize the current literature on the topic of transgender men desiring reproduction...
Insulin Sensitivity Improves with Testosterone Therapy in Men with Type 2 Diabetes and Hypogonadism
About a third of men with type 2 diabetes (T2D) also have hypogonadotropic hypogonadism (HH). This comorbidity makes that subgroup more insulin resistant, with increased adiposity and less lean mass, according to research published recently in The Journal of Clinical Endocrinology & Metabolism. A team led by Paresh Dandona, BSc, MB, BS, DPhil, FRCP, of...
As men age, testosterone levels decrease, but current guidelines recommend testing in symptomatic men only, and there has been a lack of consensus about what point that decrease becomes a deficiency. Healthy aging men have been presumed to have higher serum testosterone levels than their counterparts with obesity, smoking history, or associated comorbidities, but large-scale...
Testosterone supplementation prevents an increase in circulating ghrelin but does not appear to affect appetite or energy intake in healthy men who are suffering from a severe, short-term energy deficit, according to a study recently published in the Journal of the Endocrine Society. Researchers led by J. Philip Karl, PhD, RD, and Stefan M. Pasiakos,...
Burning Questions: Are E-Cigarettes Safer than Traditional Cigarettes for Pregnant Women?
While the health risks linking tobacco use by pregnant woman has been long understood, vaping presents a new frontier. A recent mouse study from the Journal of the Endocrine Society appears to show that there are some definite ill effects of e-cigarettes and the health of the offspring. We’ve known for decades about the health...
As endocrine science unlocks more secrets of endocrine disruptors, new common household items are being scrutinized for their safety. A recent study from The Journal of Clinical Endocrinology & Metabolism reveals how lavender oil – a staple in Hispanic culture – could possess estrogenic and antiandrogenic consequences. In some U.S. Hispanic communities, liberal use of...
Review Examines Optimal Care for Patients with 46,XY Differences of Sex Development
Treating patients with 46,XY differences of sex development (DSD) will require interdisciplinary healthcare teams trained to care for patients and their families, according to a paper recently published in Endocrine Reviews. The review, by Amy B. Wisniewski, of Oklahoma State University in Stillwater, et al., points out that DSD are a heterogenous group of congenital...
