Fibroblast growth factor 21 (FGF21) protects mice against ethanol-induced loss of balance and righting reflex, according to a study recently published in Cell Metabolism. Researchers led by Steven Kliewer, PhD, and David Mangelsdorf, PhD, both of the University of Texas Southwestern Medical Center in Dallas, point out that simple sugars in ripening fruits and nectars are a...
Book Review: The Healthiest Diet for You: Scientific Aspects
At a time when we are overwhelmed by all kinds of misinformation about our diet, and one nutritional fad follows another at an incredibly fast pace, The Healthiest Diet for You: Scientific Aspects focuses on the latest scientific data regarding nutrition, metabolism, exercise, and genetics, which are the key components of personalized nutrition and healthy...
Women with obesity may share risk for the disease with their daughters, but not their sons, according to a new study published in The Journal of Clinical Endocrinology & Metabolism. Obesity is a common, serious and costly disease affecting nearly half of the adults and 20% of children in the United States. It costs an estimated $173 billion...
Rebound Weight Gain in Children with Obesity Linked to Disconnect between Brain and Gut
Children with obesity who have recently lost weight are more likely to show hunger-related activity in their brains after a meal, according to research presented at the 60th Annual European Society for Paediatric Endocrinology Meeting. This brain activity, reflecting that they were unsatisfied by their meal, happens even though their gut hormone levels have changed, as...
Are Pregnant Women with Obesity and Diabetes More Likely to Have a Child with ADHD?
Study only finds this association in women with excessive weight gain during pregnancy Children of women with gestational diabetes and obesity may be twice as likely to develop attention-deficit/hyperactivity disorder (ADHD) compared to those whose mothers did not have obesity, according to new research published in The Journal of Clinical Endocrinology & Metabolism. The estimated number of children...
Mere Sight of a Meal Triggers Inflammatory Response in the Brain
Researchers from the University of Basel and University Hospital Basel have identified how the sensory perception of a meal generates a signal to the pancreas to ramp up insulin production: inflammatory factor interleukin 1 beta (IL1β), which is also involved in the immune response to pathogens or in tissue damage. The team reported their findings...
People with sedentary lifestyles and unhealthy sleep behaviors could develop fatty liver disease, according to new research published in The Journal of Clinical Endocrinology & Metabolism. Fatty liver disease is the leading chronic liver disease worldwide, affecting about a quarter of the adult population. This type of liver disease is fueled by metabolic disorders such...
Mouse Study Finds FGF21 Directs Body’s Responses to Low-Protein Diet
Reducing the amount of protein in the diet produces an array of favorable health outcomes, including an extension of lifespan, and that these effects depend on Fibroblast Growth Factor 21 (FGF21), according to a study recently published in Nature Communications. It has long been known that reducing the amount you eat improves health and extends...
