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Tumor size and random growth hormone concentration at diagnosis are the best predictors for remission of acromegaly after transsphenoidal surgery (TSS), according to a study recently published in The Journal of Clinical Endocrinology & Metabolism. Researchers led by Eva C. Coopmans, MD, of Erasmus University Medical Center in Rotterdam, The Netherlands, point out that TSS...
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Machine learning (ML), a type of artificial intelligence, could be used to predict how patients with acromegaly respond to first-generation somatostatin receptor ligands (fg-SRLs), according a study recently published in The Journal of Clinical Endocrinology & Metabolism. Researchers led by Mônica Gadelha, MD, PhD, of the Endocrine Unit and Neuroendocrinology Research Center at the Medical...
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Last month, Endocrine News ran a feature about the need optimal glycemic control in patients hospitalized with COVID-19, which could require physicians treating these patients to take different approaches than usual. Now, an international group of healthcare experts have developed an app to help the providers on the front lines of caring for patients with...
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Consuming sucralose-sweetened beverages with carbohydrates may impair insulin sensitivity, according to a study recently published in Cell Metabolism. Researchers led by Dana M. Small, PhD, director of the Modern Diet and Physiology Research Center at Yale University in New Haven, Conn., point out that there is still significant controversy surrounding the effects of no- or...
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A pancreatic cancer “time machine” has revealed that the disease is even more unpredictable than previously thought: Cancer cells promote each other’s invasiveness when they grow together, according to a paper recently published in Small. Researchers led by Stephen Konieczny, PhD, professor of biological sciences at Purdue University, and Bumsoo Han, PhD, professor of biomedical...
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Testosterone supplementation prevents an increase in circulating ghrelin but does not appear to affect appetite or energy intake in healthy men who are suffering from a severe, short-term energy deficit, according to a study recently published in the Journal of the Endocrine Society. Researchers led by J. Philip Karl, PhD, RD, and Stefan M. Pasiakos,...
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Exposure to bisphenol A (BPA), even at environmentally low doses, disrupts the preovulatory luteinizing hormone (LH) surge and leads to abnormal estrous cycle and folliculogenesis, according to a study recently published in Endocrinology. This disruption is reversible following adult exposure, but it persists into adulthood after neonatal exposure. Researchers led by David Lopez-Rodriguez, MSc, at the neuroendocrinology...
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Treating patients with 46,XY differences of sex development (DSD) will require interdisciplinary healthcare teams trained to care for patients and their families, according to a paper recently published in Endocrine Reviews. The review, by Amy B. Wisniewski, of Oklahoma State University in Stillwater, et al., points out that DSD are a heterogenous group of congenital...
