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Eureka 2023! Part I: Top Endocrine Discoveries

For the ninth year running, Endocrine News talks to editors from Endocrine Society publications to unearth the endocrine nuggets of 2023. Here, the editors of the Endocrine Reviews weigh in on what they think qualify as the year’s biggest discoveries in endocrine science. The endocrine Gold Rush of ’22 from last year’s issue might have...
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Researchers Observe Beta-Arrestin’s Mechanism in GPCRs

Beta-arrestins attach themselves to outer cell membranes, waiting for hormones or neurotransmitters to land on receptors – an unexpected and surprising finding recently published in Cell. Researchers led by Davide Calebiro, MD, professor of Molecular Endocrinology in the Institute of Metabolism and Systems Research at the University of Birmingham and Co-Director of the Centre of...
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Mouse Study Hints at Specific Brain Receptor behind PCOS Symptoms

Deletion of androgen receptors (ARs) in leptin receptor (LepRb) neurons improves estrous cycles, providing a possible therapeutic target for the symptoms of polycystic ovarian syndrome (PCOS), according to a mouse study recently published in Endocrinology. Researchers led by Carol F. Elias, PhD, of the University of Michigan Medical School’s Department of Molecular and Integrative Physiology,...
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Hormone Discovery Could Predict Long Term Health of Men

Scientists from the University of Nottingham have discovered that the novel insulin-like peptide hormone INSL3 is consistent over long periods of time and is an important early biomarker for prediction of age-linked disease and published their findings in Frontiers in Endocrinology.  Researchers led by Richard Ivell, PhD, and Ravinder Anand-Ivell, PhD, FRSB, point out that...
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Repainting the Pituitary Landscape

Always mystifying and bit mysterious, the pituitary is the gland that sends out the orders to the other glands in the body, from regulating the adrenals and the thyroid to coordinating reproduction. However, thanks to a worldwide collaboration and a new database, this “master gland” is slowly but surely unlocking its secrets. The pituitary –...