Directed differentiation of human induced pluripotent (hiPSCs) into Leydig-like cells may be a novel and promising treatment for late-onset hypogonadism (LOH), according to a study recently published in Endocrinology. Researchers led by Takashi Aoi, MD, PhD, of Kobe University in Japan, point out that LOH is characterized by various symptoms, including erectile dysfunction, decreased muscle...
Review Examines Relationship Between Gestational Diabetes and Offspring Fertility
A review recently published in Endocrinology offers some new insights on how maternal obesity-associated gestational diabetes (GDM) affects the reproductive health of offspring, discussing possible mechanisms, the latest perceptions, and highlighting areas that need further investigation. The review, by Niharika Sinha, PhD; Gretchen Lydia Walker; and Aritro Sen, PhD, all of Michigan State University in...
COVID-19 Pandemic Associated with Disruptions to Women’s Reproductive Health
Women’s reproductive health has been disrupted as a result of the psychological burden of the COVID-19 pandemic, and affected women need additional medical and psychological support, according to research presented at the Society for Endocrinology annual conference in Edinburgh last November. The findings indicate that stress and sleep disturbance related to the pandemic have had...
Stress From Rising Population Numbers May Cause a Decline in Human Fertility
A predicted population drop at the end of the century could be explained by stress from meaningless social interactions, according to a review article published in the Endocrine Society’s journal, Endocrinology. Researchers predict a peak in population numbers in 2064 followed by a 50% drop by the end of the century from changes in human reproductive behavior and function. There has been a 50% decrease in...
Two studies from the all-virtual ENDO 2021 focused on how pregnancy is impacted by endocrine-disrupting chemicals. From both ends of the umbilical cord, research shows that both mothers and offspring feel the effects of these chemicals, sometimes for generations to come. In 2009, the Endocrine Society’s first Scientific Statement on endocrine-disrupting chemicals (EDCs) was...
Endocrine-disrupting chemicals (EDCs) may influence hormonal shifts during pregnancy as well as contribute to postpartum depression, according to a small study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism. Postpartum depression is a serious and common psychiatric disorder that affects up to one in five childbearing women. The cause of postpartum depression...
Factors Other than Gestational Weight Gain Linked to Metabolic Complications of Pregnancy
Factors other than how much weight a woman gains during pregnancy may contribute to metabolic complications such as gestational diabetes (GDM), according to a paper recently published in Journal of the Endocrine Society. Researchers led by Fernanda L. Alvarado, MD, of the Mother Infant Research Institute at Tufts Medical Center in Boston, Mass., point out...
New study shows girls with excess body fat developed fully mature breasts more slowly but started their period sooner. Puberty looks different, in terms of both reproductive hormones and breast maturation, in girls with excess total body fat, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism. Previous...
