Positive top-line results this week were announced from the multinational, pivotal Phase 3 SONICS study evaluating levoketoconazole for the treatment of endogenous Cushing’s syndrome. Strongbridge Biopharma is marketing the drug as RECORLEV™ . The open-label, single-arm SONICS study achieved statistical significance of its pre-specified primary endpoint, with 30 percent of patients achieving normalization of mean urinary...
Researchers have shown that somatic USP8 gene mutations are a common cause of pediatric Cushing disease (CD), according to a study recently published in The Journal of Clinical Endocrinology & Metabolism. The team, led by Constantine A. Stratakis, MD, of the National Institutes of Health in Bethesda, Md., point out that this mutation has been...
Female athletes and women who have eating disorders are prone to developing a condition called hypothalamic amenorrhea that causes them to stop menstruating. The Endocrine Society today issued a Clinical Practice Guideline advising healthcare providers on ways to diagnose and treat this condition. The guideline, titled “Functional Hypothalamic Amenorrhea: An Endocrine Society Clinical Practice Guideline,”...
Society Issues Clinical Practice Guideline on Hypopituitarism
The Endocrine Society today issued a Clinical Practice Guideline that recommends treating insufficient hormone levels in individuals with hypopituitarism by replacing hormones at levels as close to the body’s natural patterns as possible. The guideline, titled “Hormonal Replacement in Hypopituitarism in Adults: An Endocrine Society Clinical Practice Guideline,” was published online and will appear in...
Members in the News: John W. Funder Awarded Fondation IPSEN Endocrine Regulations Prize
Endocrine Society member John W. Funder, MD, PhD, of Prince Henry’s Institute in Victoria, Australia, today was awarded the Fondation PSEN Endocrine Regulations Prize for his work on endocrine aspects of hypertension, including primary aldosteronism. The award was presented at the International Congress of Endocrinology — Chinese Society of Endocrinology in Beijing. As Business Wire points out, Funder...
- Adrenal
- Bone and Mineral
- Diabetes Research Articles
- Head Glands
- Reproductive Issues
- Thyroid News and Research Articles
Eureka! Top Endocrinology Discoveries of 2015: A Year in Review
Endocrine News has compiled the leading breakthroughs in endocrine research over the course of the past year with the help from 11 editors from Endocrine Reviews. From genetic research to new thyroid cancer drugs, amazing progress is being made in the field of endocrinology. Each year brings us a little closer to solving complex endocrine...
When radio personality Froggy was diagnosed with acromegaly 10 years
ago, he made it his personal mission to educate the public — as well as
primary care physicians — on this rare and unexpected disease.Uncommon Knowledge: Advancing Medical Therapy of Pituitary Tumors
A clinical researcher, a basic researcher and a clinical practitioner discuss pituitary tumors and a new “revolution” occurring in their treatment. In the last four decades, endocrinologists have witnessed a small revolution in the medical therapy of pituitary tumors. Starting with the fi rst reports on the effi cacy of bromocriptine in the treatment of...
