Low Blood Sugar Poses Unaddressed Threat to People with Type 2 Diabetes
Endocrine Society analysis identifies hypoglycemia as an ongoing gap in diabetes care New research from the Endocrine Society and Avalere Health finds that clinicians lack the resources to identify, assess and manage patients who are at a high risk of developing hypoglycemia, or episodes of dangerously low blood sugar. The analysis was published in The Journal...
Digging for Answers: Controlling Diabetic Microvascular Disease
Diabetic microvascular disease threatens myriad complications, even as researchers continue to make progress in understanding the underlying mechanisms. According to a new scientific statement from the Endocrine Society, glycemic control remains the key. “Vascular complications are the major cause of morbidity and mortality in diabetic patients,” according to a new Endocrine Society scientific statement...
A Heart to Heart Talk: The Statin Intolerance Controversy at ENDO 2018
As ENDO 2018 in Chicago quickly approaches, we thought a preview of a heart-specific session would be ideal for this month’s issue, especially since it coincides with American Heart Month and Valentine’s Day. The University of Kentucky’s Lisa Tannock, MD, gives us the details about her Meet the Professor session on statin intolerance and explains...
Dulaglutide significantly improves A1C (average blood sugar concentration over two to three months) when added to ongoing treatment with a sodium-glucose co-transporter-2 (SGLT-2) inhibitor, according to results from AWARD-10, a new Phase 3b clinical study.1 These data were published online first in The Lancet Diabetes & Endocrinology. “I’ve seen in my practice that even with...
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Reduced Time in Hypoglycemia Demonstrated in Recent Insulin Pump Trial
Positive results were announced this week from the study of a new insulin pump with a predictive low glucose suspend (PLGS) feature. Data showed that the system achieved the primary outcome of reducing time spent in hypoglycemia compared to sensor-augmented pump therapy alone. The company developing the device, Tandem Diabetes Care, is marketing its new...
Pulmonary Function Should Be Target in Diabetes Care, Researchers Report
Doctors treating patients with type 2 diabetes should consider pulmonary function when providing care to these patients, according to a paper recently published in Endocrine Reviews. The review, by Albert Lecube, of the Universitat de Lleida, Spain, et al, points out that the lung is not usually included in the list of organs affected by...
NIDDK Releases Funding Opportunity Announcements for Type 1 Diabetes Research
On February 15, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) released 17 long-awaited Funding Opportunity Announcements (FOAs) to support a variety of research projects related to type 1 diabetes and its complications. These FOAs are supported with the recent $150 million extension of the Special Statutory Funding Program for Type 1...
Clock Protein Controls Daily Cycle of Gene Expression by Regulating Chromosome Loops, Study Finds
The up-and-down daily cycles of a long-studied clock protein called Rev-erb coordinates the ebb and flow of gene expression by tightening and loosening loops in chromosomes, according to new research from the Perelman School of Medicine at the University of Pennsylvania. The findings appear online this week in Science First Release. Over the last 15-plus years, a team led by the...
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