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Digging for Answers: Controlling Diabetic Microvascular Disease

Digging_796332061 Diabetic microvascular disease threatens myriad complications, even as researchers continue to make progress in understanding the underlying mechanisms. According to a new scientific statement from the Endocrine Society, glycemic control remains the key.   “Vascular complications are the major cause of morbidity and mortality in diabetic patients,” according to a new Endocrine Society scientific statement...
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New Data Show Dulaglutide in Combination with an SGLT-2 Inhibitor Improves Blood Sugar Control in People with Type 2 Diabetes

Dulaglutide significantly improves A1C (average blood sugar concentration over two to three months) when added to ongoing treatment with a sodium-glucose co-transporter-2 (SGLT-2) inhibitor, according to results from AWARD-10, a new Phase 3b clinical study.1 These data were published online first in The Lancet Diabetes & Endocrinology. “I’ve seen in my practice that even with...
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Reduced Time in Hypoglycemia Demonstrated in Recent Insulin Pump Trial

Positive results were announced this week from the study of a new insulin pump with a predictive low glucose suspend (PLGS) feature. Data showed that the system achieved the primary outcome of reducing time spent in hypoglycemia compared to sensor-augmented pump therapy alone. The company developing the device, Tandem Diabetes Care, is marketing its new...
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NIDDK Releases Funding Opportunity Announcements for Type 1 Diabetes Research

On February 15, the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) released 17 long-awaited Funding Opportunity Announcements (FOAs) to support a variety of research projects related to type 1 diabetes and its complications. These FOAs are supported with the recent $150 million extension of the Special Statutory Funding Program for Type 1...
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Clock Protein Controls Daily Cycle of Gene Expression by Regulating Chromosome Loops, Study Finds

The up-and-down daily cycles of a long-studied clock protein called Rev-erb coordinates the ebb and flow of gene expression by tightening and loosening loops in chromosomes, according to new research from the Perelman School of Medicine at the University of Pennsylvania. The findings appear online this week in Science First Release. Over the last 15-plus years, a team led by the...

Diabetes Research Articles

Get the most up to date news on diabetes research and treatment. For more information read the latest issue of Endocrine News.