Researchers have identified fasting hyperinsulinemia as a primary, yet often overlooked, driver of metabolic dysfunction-associated steatotic liver disease (MASLD). A new review published in Hepatology suggests that elevated insulin levels are not merely a symptom of metabolic syndrome but a direct contributor to liver fibrosis and a potent predictor of major adverse liver and cardiovascular...
A mouse study found that a father’s nicotine exposure can affect the offspring’s ability to process sugar and may contribute to diabetes risk, according to new research published in the Journal of the Endocrine Society. An estimated 40.1 million people in the United States have diabetes, according to the U.S. Centers for Disease Control and Prevention. Having diabetes...
A significant retrospective cohort study has revealed that even mild levels of glucose intolerance during pregnancy are associated with a higher risk of obesity in children as they reach adolescence. The research, published in The Journal of Clinical Endocrinology & Metabolism, suggests that the in utero environment may play a more critical role in long-term...
For the eleventh year running, Endocrine News talks to editors from Endocrine Society publications to unearth the most impressive breakthroughs in endocrine science and research for 2025. From GLP-1s, adrenal treatments, and acromegaly breakthroughs to obesity, diabetes, and cutting-edge research in reproductive medicine, 2025 was a banner year for endocrine research and researchers! For more...
New research shows that that the diabetes/obesity medication tirzepatide can cause clinically meaningful improvements in blood sugar control and weight loss in children and adolescents with type 2 diabetes aged 10-17 years whose diabetes and weight are inadequately controlled with an existing treatment regimen of metformin, insulin, or both. The study (the SURPASS-PEDS trial), led...
New research reveals long-term bone health implications Research presented at ENDO 2025 suggests that adolescents with both obesity and type 2 diabetes could be at a higher risk for fractures and osteoporosis later in life. Lead researcher Fida Bacha, MD, discusses her group’s findings as well as the impact of insulin resistance and hyperglycemia on...
A recently published Scientific Statement sheds light on new and improved treatment options for type 1 diabetes. Endocrine News speaks with first author Aaron W. Michels, MD, about the Statement’s implications and why this is an exciting time in type 1 diabetes research. In July, the Endocrine Society published a Scientific Statement that highlights potential...
On behalf of the Endocrine Society’s Early-Career Special Interest Group (SIG), Milay Luis Lam, MD talks with Early-Career SIG steering group member, Manasi Shah, MD, on bringing science to the transplant bedside and discusses her endocrine journey from her native Mumbai, India, to conducting clinical trials in the U.S. You could say that treating people...