The up-and-down daily cycles of a long-studied clock protein called Rev-erb coordinates the ebb and flow of gene expression by tightening and loosening loops in chromosomes, according to new research from the Perelman School of Medicine at the University of Pennsylvania. The findings appear online this week in Science First Release. Over the last 15-plus years, a team led by the...
Researchers in South Africa have shown that regularly drinking sugar-sweetened beverages (SSBs) contributes to the development of diabetes, high blood pressure, metabolic syndrome, and other endemic health problems, according to a review recently published in the Journal of the Endocrine Society. The review’s authors, led by M. Faadiel Essop, PhD, of Stellenbosch University in Stellenbosch,...
In utero exposure to a high-fat diet reprograms the liver, leads to long-term gene dysregulation, and ultimately to metabolic disease, according to the results of an animal study recently published in Endocrinology. Researchers led by Maureen J. Charron, PhD, of Albert Einstein College of Medicine in the Bronx, N.Y., point out that it’s already known...
Inflammatory processes in the liver lead to elevated cholesterol levels in people with diabetes, thus promoting subsequent vascular diseases, according to a study by researchers at Helmholtz Zentrum München, Technische Universität München (TUM) and the Collaborative Research Center SFB 1118 at Heidelberg University Hospital. The paper was recently published in Cell Reports. “Even if blood...
An endocrinologist and cardiologist teamed up to create an entertaining and easily understood method to educate patients. The result is Doctablet, a series of online animations that patients of all ages, backgrounds, and education levels can comprehend and even enjoy. A lack of quality time with patients is a problem in endocrinologists’ offices — and...
New Israeli study shows even BMIs in normal range associated with increased cardiovascular risk While there is solid evidence that adolescent overweight and obesity are associated with coronary heart disease (CHD) and stroke, less is known about the association between body mass index (BMI) and rarer cardiovascular diseases. A new large-scale, 45-year Israeli study published...
A study from Emory University published in the April 2017 issue of Journal of Diabetes and Its Complications observes a near-20% reduction in perioperative complications, a 1.2-day reduction in ICU stay, and a $3,654 reduction in per-patient hospitalization costs for coronary artery bypass graft (CABG) surgery. The reported outcomes, which included no severe hypoglycemia less...
In yet another blow to the idea that there are “metabolically healthy” obese people, Danish researchers have found that obesity carries with it a higher risk of ischemic heart disease (IHD), irrespective of metabolic health, according to a study recently published in The Journal of Clinical Endocrinology & Metabolism. Researchers led by Kristine Færch, MSc,...
An endocrinologist and cardiologist teamed up to create an entertaining and easily understood method to educate patients. The result is Doctablet, a series of online animations that patients of all ages, backgrounds, and education levels can comprehend and even enjoy. A lack of quality time with patients is a problem in endocrinologists’ offices — and...
