Late-breaking exploratory analysis from the CANVAS Program presented at the American College of Cardiology’s 67th Annual Scientific Session The results of recent analysis showed that canagliflozin significantly reduced the risk of cardiovascular (CV) death or hospitalization for heart failure (HHF) in patients with type 2 diabetes (T2D) at high CV risk. This exploratory analysis from...
Endocrine Society’s Scientific Statement examines challenges of managing obesity Whether you pick low-carb, low fat or another diet plan, scientific research indicates each can help some people achieve modest long-term weight loss with potential improvement in health risks, according to the Scientific Statement the Endocrine Society issued today on managing obesity. The authors found the...
A new study shows that heavier adolescents may have an increased risk of succumbing to a cardiovascular event death in middle age. What can be done earlier in life to forestall these events and should researchers take another look at what constitutes an ideal body mass index for kids? February is American Heart Month and...
As ENDO 2018 in Chicago quickly approaches, we thought a preview of a heart-specific session would be ideal for this month’s issue, especially since it coincides with American Heart Month and Valentine’s Day. The University of Kentucky’s Lisa Tannock, MD, gives us the details about her Meet the Professor session on statin intolerance and explains...
The up-and-down daily cycles of a long-studied clock protein called Rev-erb coordinates the ebb and flow of gene expression by tightening and loosening loops in chromosomes, according to new research from the Perelman School of Medicine at the University of Pennsylvania. The findings appear online this week in Science First Release. Over the last 15-plus years, a team led by the...
Researchers in South Africa have shown that regularly drinking sugar-sweetened beverages (SSBs) contributes to the development of diabetes, high blood pressure, metabolic syndrome, and other endemic health problems, according to a review recently published in the Journal of the Endocrine Society. The review’s authors, led by M. Faadiel Essop, PhD, of Stellenbosch University in Stellenbosch,...
In utero exposure to a high-fat diet reprograms the liver, leads to long-term gene dysregulation, and ultimately to metabolic disease, according to the results of an animal study recently published in Endocrinology. Researchers led by Maureen J. Charron, PhD, of Albert Einstein College of Medicine in the Bronx, N.Y., point out that it’s already known...
Inflammatory processes in the liver lead to elevated cholesterol levels in people with diabetes, thus promoting subsequent vascular diseases, according to a study by researchers at Helmholtz Zentrum München, Technische Universität München (TUM) and the Collaborative Research Center SFB 1118 at Heidelberg University Hospital. The paper was recently published in Cell Reports. “Even if blood...