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Phase 3 Trial Shows Lonapegsomatropin Is Superior to Somatropin in Treatment-Naïve Children with Growth Hormone Deficiency

The investigational long-acting, once-weekly prodrug lonapegsomatropin (TransCon hGH) may be more beneficial to treatment-naïve pediatric patients with growth hormone deficiency (GHD) than daily somatropin of equivalent weekly dose, according to a paper recently published in The Journal of Clinical Endocrinology & Metabolism. Researchers led by Aimee D. Shu, MD, of Ascendis Pharma (who funded the...
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Research Shows Employer-Based Weight Management Program with Access to Anti-Obesity Medications Results in Greater Weight Loss

A Cleveland Clinic study demonstrates that adults with obesity lost significantly more weight when they had access to medications for chronic weight management in conjunction with their employer-based weight management program, compared to adults who did not have access to the medications. The study was published in JAMA Network Open.   Obesity is a complex disease that...
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Patients Report Long-Term Favorable Effects of Weight Loss Surgery in Their Daily Lives

A new analysis from the STAMPEDE trial shows that over the course of five years, patients who had bariatric and metabolic surgery to treat uncontrolled type 2 diabetes reported greater physical health, more energy, less body pain, and less negative effects of diabetes in their daily lives, compared with patients who had medical therapy alone...
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HIV-1 Establishes “Sanctuary Site” In the Testis by Disrupting Blood-Testis Barrier Function

HIV-1, the most common type of human immunodeficiency virus, invades the testis and is able to avoid combination antiretroviral (cART) drugs by permeating the blood-testis barrier (BTB) and perturbing BTB function, potentially through the Tat protein, according to a study recently published in Endocrinology. Researchers led by C. Yan Cheng, PhD, senior scientist at The...
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Members in the News: Joshua Klopper, MD, Named Veracyte’s Medical Director of Endocrinology

Endocrine Society member Joshua Klopper, MD, has been appointed medical director of Endocrinology at the genomic diagnostics company Veracyte.  Klopper is a nationally recognized endocrinologist who specializes in the evaluation and management of thyroid nodules and thyroid cancer. He joins Veracyte today, reporting to another Society member, Richard T. Kloos, MD, Veracyte’s executive medical director....
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Dosage Flexibility of Liquid Hypothyroidism Treatment Introduced for Patients and Clinicians

Americans diagnosed with hypothyroidism and their clinical providers now have access to greater dosage flexibility within levothyroxine therapy, with three new dosage strengths of levothyroxine sodium oral solution now available to treat hypothyroidism. IBSA Pharma markets the drug as Tirosint®-SOL. The unique new dosing options – 37.5, 44 and 62.5 micrograms – are a first...