Author: Derek Bagley
Women Face Greater Risk of Obesity in Low- and Middle-Income Countries
Study finds women are 2-3 times more likely to be affected than men Women in low- and middle-income countries, especially in the Sub-Saharan Africa region, may be 10 times more likely to have obesity or heart health issues than their male counterparts, according to a large meta-analysis published in The Journal of Clinical Endocrinology and Metabolism....
Lonapegsomatropin Provides Height Improvements in Later Tanner Stages without Increase in Dose
Lonapegsomatropin, a once-weekly prodrug of somatropin, can help children in Tanner Stages 3-5 maintain consistent height standard deviation scores (SDS) without an increase in the mean dose, according to a study presented at ENDO 2023. Ascendis Pharma is marketing the drug as TransCon hGH. Researchers led by Paul Hofman, MD, FRACP, of the Liggins Institute...
Children with Achondroplasia See Improved Annual Height Velocity with Investigational Prodrug
Children with achondroplasia (ACH), the most common form of hereditary short stature, experienced statistically significant improvements in their annual height velocity with the prodrug TransCon CNP, according to a study presented at ENDO 2023. Ascendis Pharma is investigating the drug in the Phase 2 ACcomplisH trial. Researchers led by Ravi Savarirayan, MBBS, FRACP, MD, of...
COVID-19 Vaccines and Hyperglycemia in Patients with Type 1 Diabetes
While proven to be safe, the COVID-19 vaccines could cause some people with type 1 diabetes to see their blood sugar to temporarily spike. The key for both patient and provider is to remain vigilant with glucose testing and insulin dosing post-jab to maintain glycemic control. In the summer of 2021, a 24-year-old woman presented...
United Kingdom scientists will have access to the world’s largest research collaboration program, Horizon Europe, as the Prime Minister secures a bespoke deal with improved financial terms for the UK’s participation. UK researchers can now apply for grants and bid to take part in projects under the Horizon program, with certainty that the UK will...
Obesity Appears to Increase the Risk of Developing Polycystic Ovary Syndrome
Obesity appears to increase the risk of developing polycystic ovary syndrome (PCOS), according to a study presented at ENDO 2023. An estimated 7% to 10% of all reproductive-aged women globally have PCOS. Women with PCOS have a hormonal imbalance and metabolism problems that may affect their overall health, appearance, and fertility. PCOS is associated with health...
Duration and Poor Quality of Sleep Associated with Greater Risk for Diabetes
Fewer than six hours or more than 10 hours of sleep, and poor quality of sleep are associated with a greater risk for diabetes, according to research presented at ENDO 2023. Previous studies have looked at poor sleep quantity and quality, and its impact on the risk for diabetes or obesity. However, this study sought...