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Saliva Test One Step Closer to Replacing Blood Work for Adrenal Disorder Diagnosis

Salivary cortisol and cortisone can be valuable tools in diagnosing adrenal insufficiency (AI), offering non-invasive options for screening and potentially avoiding the need for ACTH stimulation tests in some cases, states a recent study in The Journal of Clinical Endocrinology and Metabolism. Adrenal insufficiency (AI), such as in cases of Addison’s disease and Congenital Adrenal Hyperplasia,...
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Easy Targets: How Endocrine-Disrupting Chemicals Affect Reproductive Endocrinology

Veiga-Lopez_Almudena-cropped-600x676 Endocrine-disrupting chemicals have been implicated in a wide range of poor health outcomes, including infertility and obesity. Endocrine News speaks to Almudena Veiga-Lopez, DVM, PhD, the chair of an upcoming ENDO 2025 symposium on these chemicals’ effects on reproductive organs, which are particularly vulnerable to EDCs. Endocrine-disrupting chemicals are everywhere, and there is seemingly no...
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Hidden Steroids in Arthritis Supplements Raise Serious Adrenal Concerns

JES cover Before you reach for that arthritis supplement, take note: Over-the-counter supplements could contain surreptitious glucocorticoids, notes a new case series study published in The Journal of The Endocrine Society. The study describes 12 patients who developed Cushing syndrome (CS) and/or adrenal insufficiency (AI) after consuming commonly used supplements such as Artri King, Ardosons, and Ajo...
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Sriram Gubbi of NIDDK Wins Endocrine Society’s 2025 Endocrine Images Art Competition 

SGubbi headshot for ENDO 2025 “Cosmic Bubble” image features cells from a thyroid cancer subtype  Sriram Gubbi, MD, won the Endocrine Society’s 2025 Endocrine Images Art Competition with his microphotograph of follicular thyroid carcinoma cells titled “The Cosmic Bubble”.   The art competition celebrates the beauty of endocrine science as seen through the lens of a microscope. More than 30 entries...
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Health Challenges in Males with Classic Adrenal Hyperplasia

jcem_110_1cover Males diagnosed with classic congenital hyperplasia (CAH) due to 21-hydroxylase deficiency require lifelong treatment, with adolescence the most challenging treatment period, notes a review article in The Journal of Clinical Endocrinology & Metabolism and a supplement sponsored by Neurocrine Biosciences, Inc., an American biopharmaceutical company that develops for neurological and endocrine-related disorders. To replace the...
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FDA Files New Drug Application for Relacorilant as Treatment for Patients With Hypercortisolism

Last month Corcept Therapuetics Incoporated announced that the U.S. Food and Drug Administration (FDA) filed its New Drug Application (NDA) submission for the company’s proprietary, selective cortisol modulator, relacorilant, to treat patients with endogenous hypercortisolism (Cushing’s syndrome). Corcept’s NDA is based on positive results from the pivotal GRACE trial and confirmatory evidence from the Phase 3 GRADIENT...