When two very different pediatric patients with obesity presented with unusually high leptin levels, endocrine researchers took notice and discovered that leptin was not adequately binding with receptors. When the young patients’ familial history was considered, solutions were finally forthcoming. About three years ago, a 19-month-old girl presented to Sidra Medicine – a women’s and...
With springtime just around the corner (or perhaps still a little further around the corner if you live in Rochester, N.Y., like I do), our thoughts once again turn to sunshine, flowers, and ENDO! This year’s annual meeting in Boston, Massachusetts, June 1-4, promises to be one of our best yet. Members of the dedicated...
Two recent studies from The Journal of Clinical Endocrinology & Metabolism emphasize the negative metabolic effects of fat mass compared with lean muscle mass on adolescent cardiovascular health and bone health. Several recent studies have highlighted the importance of lean muscle mass versus the dangers of fat mass in children and adolescents — and suggest...
An Endocrine News roundup of the week’s pharmaceutical news, breakthroughs, and general information. * Topline Results Announced for CAH Studies On March 13, Spruce Biosciences announced topline results from its CAHmelia-203 study of tildacerfont in adult classic congenital adrenal hyperplasia (CAH) and its CAHptain-205 study of tildacerfont in pediatric classic CAH. Spruce is investigating tildacerfont,...
Bariatric surgery may result in significant cardiometabolic improvements, particularly among younger, female, or white people and those without comorbidities, according to new research published in the Journal of the Endocrine Society. The United States has the highest obesity rates globally. In 2017 – 2018, about 40% of U.S. adults had obesity and 9% had severe obesity. The prevalence is...
When Evan D. Rosen, MD, PhD, first began researching adipose biology many years ago, not much was known about it and its impacts on so many diseases. He talks to Endocrine News about how far the science has advanced regarding adipose tissue as well as his own lab’s research, the importance of collaboration, and why...
Laurence Katznelson, MD, a national leader in graduate medical education and a distinguished physician-scientist in endocrinology and metabolism, will join Cedars-Sinai as vice dean of Medical Education on May 1. Katznelson will oversee Cedars-Sinai’s Graduate Medical Education, Continuing Medical Education, the Women’s Guild Simulation Center for Advanced Clinical Skills, the Chuck Lorre School of Allied Health, and...
The Endocrine Society applauds Congress for approving the first funding increase for the Special Diabetes Program in two decades. The U.S. Senate voted Friday March 8 to extend the program, which supports both diabetes care and research into type 1 diabetes, until the end of 2024. This is part of the six-bill package funding several...