A new preoperative molecular malignancy classifier for identifying BRAF V600E mutation status among thyroid nodule biopsies has been shown to be clinically valid, according to a study recently published in Proceedings of the Pacific Symposium on Biocomputing. The data from the study show that the classifier detects the BRAF V600E mutation — often predictive of...
Tachykinin-Kisspeptin System’s Role in Reproduction Identified Researchers may have identified a system that acts as a central coordinator for reproduction, according to a paper recently published in Endocrinology. Investigators led by Victor M. Navarro, PhD, of Brigham and Women’s Hospital and Harvard Medical School, noted that the mechanisms that control kisspeptin release have become a...
New Drug Approved to Treat GEP-NETs The U.S. Food and Drug Administration recently approved a drug called Somatuline® Depot® (lanreotide) Injection 120mg for the treatment of gastroenteropancreatic neuroendocrine tumors (GEP-NETs) in adult patients with unresectable, well- or moderately differentiated, locally advanced, or metastatic disease to improve progressionfree survival. GEP-NETs are a rare type of cancer,...
UNLIGANDED THYROID HORMONE RECEPTOR May Play Role in Development A novel animal study has uncovered clues to embryo developmental timing and growth rates. Th e study, recently published in Endocrinology, should prompt further research and improve the understanding on the role of the thyroid hormone (T3) signaling pathway during early development, according to lead author...
GOUT Associated with Diabetes Risk Gout has been independently associated with an increased risk of developing type 2 diabetes, according to a study recently published in the Annals of Rheumatic Diseases. Researchers led by Hyon K. Choi, MD, of the Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Harvard Medical School, in Boston, set...
BPA’S IMPACTS on Brain and Behavior Bisphenol A (BPA), the oft-criticized chemical found in many plastic consumer items, has been linked to brain and behavior alterations, including increased hyperactivity and stress, according to a recent rodent study, with the results published in Endocrinology. Researchers led by Heather B. Patisaul, PhD, of North Carolina State University...
LOSS OF NTRK2/KISS1R SIGNALING in oocytes Causes Premature ovarian Failure A recent mouse study may provide clues to early adult infertility, specifically premature ovarian failure (POF), a disorder that affects 1% of women of reproductive age. Researchers led by Sergio R. Ojeda, DVM, of the Oregon National Primate Research Center/Oregon Health and Science University, and...
EXPOSURES TO EDCs MAY LESSEN QUALITY OF LIFE IN FUTURE GENERATIONS Studies on rats have shown that endocrine-disrupting chemicals (EDCs) impact not only future generations, but also how these descendants respond to stress during adolescence. A new study, published in the journal Endocrinology, has revealed that the sexes differ profoundly in these effects. That is,...
