Real-World Study of More than 700,000 People with Type 2 Diabetes (T2D) Shows No Increased Risk of Below-Knee Lower Extremity Amputations with Canagliflozin Compared to Other Diabetes Medications A new real-world analysis of more than 700,000 U.S. T2D patients found no increased risk of below-knee lower extremity (BKLE) amputation with canagliflozin compared to other sodium glucose...
The following studies, among others, will be published in Endocrine Society journals. Before print, they are edited and posted online in each journal’s Early Release section. You can access the journals at www.endocrine.org. Subclinical Vascular Dysfunction Associated with Metabolic Syndrome in African Americans and Whites • Jia Shen, Joseph C. Poole, Matthew L. Topel, Aurelian...
Glucose Metabolism in High Risk Subjects for Type 2 Diabetes Carrying the rs7903146TCF7L2 Gene Variant • Giuseppe Daniele, Melania Gaggini, Mario Comassi, Cristina Bianchi, Giuseppina Basta, Angela Dardano, Roberto Miccoli, Andrea Mari, Amalia Gastaldelli, and Stefano Del Prato • In subjects at risk for T2DM, the TCF7L2 polymorphisms were associated with reduced Raex into systemic...
The following studies, among others, will be published in Endocrine Society journals. Before print, they are edited and posted online in each journal’s Early Release section. You can access the journals at www.endocrine.org. Daily or Cyclical Teriparatide Treatment in Women with Osteoporosis on No Prior Therapy and Women on Alendronate • Felicia Cosman, Jeri W....
The following studies, among others, will be published in Endocrine Society journals. Before print, they are edited and posted online in each journal’s Early Release section. You can access the journals at www.endocrine.org Relationship of Bone Metabolism Biomarkers and Periodontal Disease: The Osteoporotic Fractures in Men (MrOS) Study • Ulrike Schulze-Späte, Ryan Turner, Ying Wang,...
Glycogenin-2 Is Dispensable for Liver Glycogen Synthesis and GlucagonStimulated Glucose Release • Henrik U. Irgens, Karianne Fjeld, Bente B. Johansson, Monika Ringdal, Heike Immervoll, Sabine Leh, Oddmund Søvik, Stefan Johansson, Anders Molven, and Pål R. Njølstad • These data indicate that GN2 is not required for liver glycogen synthesis and glucagon-stimulated glucose release. Hip...
Random Blood Glucose: A Robust Risk Factor for Type 2 Diabetes • Michael E. Bowen, Lei Xuan, Ildiko Lingvay, and Ethan A. Halm • A single RBG ≥ 100 mg/ dL is more strongly associated with undiagnosed diabetes than traditional risk factors. Abnormal RBG values are a risk factor for diabetes and should be considered...
Why Does Rate of Bone Density Loss Not Predict Fracture Risk? • William D. Leslie, Sumit R. Majumdar, Suzanne N. Morin, and Lisa M. Lix • The low correlation between past and future BMD loss helps explain why the rate of BMD loss is unlikely to be helpful for refining fracture risk. A Novel Insulin...