New research challenges traditional approaches to male reproductive aging One of the posters presented as part of ENDO 2025’s Reproductive Endocrinology tract gained a lot of attention because it shed light on a heretofore unheralded link between men’s sexual well-being and metabolic health. Lead author Michael Zitzmann, MD, PhD, talks to Endocrine News about his...
U.S. FDA Approves Hydrocortisone Oral Solution for Pediatric Adrenocortical Insufficiency
The U.S. Food and Drug Administration (FDA) recently granted a New Drug Application (NDA) for a hydrocortisone oral solution Eton Pharmaceuticals, Inc. is marketing as KHINDIVI™ — a replacement therapy in pediatric patients five years of age and older with adrenocortical insufficiency. KHINDIVI is the only FDA-approved oral solution formulation of hydrocortisone. It comes in a 1mg/ml...
Rare Pediatric Case of Bilateral Adrenal Leiomyomas Highlights Diagnostic Challenges
“Bilateral Adrenal Leiomyomas in a Pediatric Patient,” a recently published case in JCEM Case Reports describes a highly unusual diagnosis in an 11-year-old boy: bilateral adrenal leiomyomas. These benign smooth muscle tumors are rare in any age group and typically occur unilaterally. The pediatric presentation, particularly affecting both adrenal glands, adds to the clinical rarity...
Doctors Recreate ‘Mini-Puberty’ to Aid Testicular Development in Male Infants with Rare Disorder
A recent systematic review published in The Journal of Clinical Endocrinology & Metabolism confirms that early hormone therapy can effectively recreate “mini-puberty” in male infants born with congenital hypogonadotropic hypogonadism (CHH) — a rare condition characterized by insufficient hormone production during early infancy. In healthy boys, a temporary surge of hormones shortly after birth —...
New Endocrine Society and European Endocrine Society guidelines provide a much-needed update Making its debut at ENDO 2025, “Diabetes and Pregnancy: An Endocrine Society and European Society of Endocrinology Joint Clinical Practice Guideline” has been long anticipated. For the first time, clinicians will have a definitive guide on treating these patients that now includes the...
Tightrope: Obesity Management in Women During Reproductive Years
As part of the ENDO 2025 session, “Obesity Management Across the Lifespan: Special Considerations,” Lisa Morselli, MD, PhD, talks about the unique challenges in obesity management in women during their reproductive years. On Tuesday, July 15, ENDO 2025 here in San Francisco will feature a session titled, “Obesity Management Across the Lifespan: Special Considerations.” As...Anti-Obesity Medications Can Normalize Testosterone Levels in Men
Anti-obesity medications can significantly raise testosterone levels and improve health outcomes for men with obesity or type 2 diabetes, according to a new study being presented Monday at ENDO 2025, the Endocrine Society’s annual meeting in San Francisco, Calif. Testosterone not only plays a critical role in the body when it comes to male sexual...
Women who work night shifts may have an increased risk for irregular periods and hormonal imbalances, according to a study being presented Monday at ENDO 2025, the Endocrine Society’s annual meeting in San Francisco, Calif. “Shiftwork-like light exposure disrupts the body’s internal timing, causing a split response where some females have disrupted reproductive cycles and...
