New research reveals long-term bone health implications Research presented at ENDO 2025 suggests that adolescents with both obesity and type 2 diabetes could be at a higher risk for fractures and osteoporosis later in life. Lead researcher Fida Bacha, MD, discusses her group’s findings as well as the impact of insulin resistance and hyperglycemia on...
A major shift is underway in women’s endocrine health that is changing how the medical community approaches Polycystic Ovary Syndrome (PCOS) and its link to cardiovascular risk. Recent findings published in the European Journal of Endocrinology, titled “Hyperandrogenaemia, Polycystic Ovary Syndrome, and Physical Fitness in Women—a Northern Finland Birth Cohort Study,” stem from a large...
New research challenges traditional approaches to male reproductive aging One of the posters presented as part of ENDO 2025’s Reproductive Endocrinology tract gained a lot of attention because it shed light on a heretofore unheralded link between men’s sexual well-being and metabolic health. Lead author Michael Zitzmann, MD, PhD, talks to Endocrine News about his...
The U.S. Food and Drug Administration (FDA) recently granted a New Drug Application (NDA) for a hydrocortisone oral solution Eton Pharmaceuticals, Inc. is marketing as KHINDIVI™ — a replacement therapy in pediatric patients five years of age and older with adrenocortical insufficiency. KHINDIVI is the only FDA-approved oral solution formulation of hydrocortisone. It comes in a 1mg/ml...
“Bilateral Adrenal Leiomyomas in a Pediatric Patient,” a recently published case in JCEM Case Reports describes a highly unusual diagnosis in an 11-year-old boy: bilateral adrenal leiomyomas. These benign smooth muscle tumors are rare in any age group and typically occur unilaterally. The pediatric presentation, particularly affecting both adrenal glands, adds to the clinical rarity...
A recent systematic review published in The Journal of Clinical Endocrinology & Metabolism confirms that early hormone therapy can effectively recreate “mini-puberty” in male infants born with congenital hypogonadotropic hypogonadism (CHH) — a rare condition characterized by insufficient hormone production during early infancy. In healthy boys, a temporary surge of hormones shortly after birth —...
New Endocrine Society and European Endocrine Society guidelines provide a much-needed update Making its debut at ENDO 2025, “Diabetes and Pregnancy: An Endocrine Society and European Society of Endocrinology Joint Clinical Practice Guideline” has been long anticipated. For the first time, clinicians will have a definitive guide on treating these patients that now includes the...
As part of the ENDO 2025 session, “Obesity Management Across the Lifespan: Special Considerations,” Lisa Morselli, MD, PhD, talks about the unique challenges in obesity management in women during their reproductive years. On Tuesday, July 15, ENDO 2025 here in San Francisco will feature a session titled, “Obesity Management Across the Lifespan: Special Considerations.” As...