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Mad Scientists: When the Scientist Becomes the Subject

Self-experimentation has a long and noble — and Nobel-winning — history in medical breakthroughs. However, due to collaborative studies and improved technology, these methods have been largely relegated to late-night movies…just ask Dr. Jekyll!  As any scientist knows, getting a new drug, device, or procedure to the human trial stage requires a Herculean effort. It...
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Lab Notes Q&A: A Peculiar Trait

Endocrine News talks to Márta Korbonits, MD, PhD, at the Queen Mary University of London about her research in seeking the mutations behind a familial adenoma. About one in every thousand individuals will develop a pituitary adenoma, a noncancerous but disruptive tumor on the pituitary gland that can induce a variety negative side effects. But,...
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Gutted: Tips and Trends in Laboratory Renovation

Whether it’s to make room for new equipment or to adhere to upgraded energy standards, if your lab hasn’t been redesigned in over a decade, you might be due for a change. Laboratories require valuable real estate, of which institutions generally have a finite amount. Scientists must often compete with peers for space to pursue...
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Q&A: When Bad Fat Goes Good

Endocrine News talks to Philip Kern, MD, at the University of Kentucky about the phenomenon of “beige” fat and what it means for the future of obesity research. Heat usually melts fat — like butter in a sunbeam — but in mammals, cold may actually burn off adipose tissue. For “brown fat,” this is no...
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Lab Notes Q&A: Genetic Mutations and Breast Cancer

Endocrine News talks to Sarat Chandarlapaty, MD, PhD, about his research on genetic mutations and breast cancer, his methods, and what impact it might have on the field of endocrinology. Estrogen-disrupting therapies such as fulvestrant and tamoxifen have achieved great success in treating breast cancer. Such drugs, which block the estrogen receptor and inhibit the...