A high-fat, high-sugar (HFHS) diet may cause obesity-related reproductive dysfunction, according to an animal study that was recently published in the Journal of the Endocrine Society. Researchers led by Natalia Toporikova, PhD, of Washington and Lee University in Lexington, Va., point out that obesity is associated with multiple metabolic and reproductive disorders, but the mechanisms...
Underactive Thyroid within Normal Range May Affect Woman’s Ability to Conceive
Study suggests even mild thyroid dysfunction may contribute to unexplained infertility New research suggests that a slightly underactive thyroid may affect a woman’s ability to become pregnant—even when the gland is functioning at the low end of the normal range, according to a study published in The Journal of Clinical Endocrinology & Metabolism. The study...
This issue highlights a special edition of ESAP, available for a limited time. Test your clinical knowledge with this free case to discover the rich intellectual legacy of endocrinology. Available on the online store. Clinical Vignette A 62-year-old man is referred for assistance in the management of hyperprolactinemia and diminished libido. Over the past 9...High Blood Pressure During Pregnancy Linked to Increased Risk of Offspring Obesity
When expectant mothers have elevated blood pressure during pregnancy, it may raise their children’s risk of developing childhood obesity, according to a study recently published in The Journal of Clinical Endocrinology & Metabolism. “Our study is the first to demonstrate that among pregnant women, elevated blood pressure is associated with a greater risk of overweight...
Review Looks at Implications of Free Testosterone Measurements
The number of testosterone prescriptions is growing, so a paper recently published in Endocrine Reviews seeks to offer some best practices for the application of free testosterone measurements in patients with androgen disorders. The paper, by Ravi Jasuja, PhD, of Harvard Medical School, et al, points out that as the number of prescriptions written for...
Study finds higher risk and earlier diagnosis of diabetes in women with PCOS Women who have polycystic ovary syndrome (PCOS) have a higher risk of developing type 2 diabetes (T2D) and are diagnosed at an earlier age with the condition, according to a new study published in The Journal of Clinical Endocrinology & Metabolism. The...
Tapering cabergoline (CAB) levels can still maintain normal prolactin (PRL) levels in patients with macroprolactinomas, according to a study recently published in the Journal of the Endocrine Society. Researchers led by Phillipe Chanson, MD, of Hopital de Bicetre in Le Kremlin-Bicetre, France, point out that CAB is “currently the dopamine agonist (DA) of choice” in...
Researchers have shown that autocrine human prolactin (hPRL) promotes endometrial tumor growth and metastasis, as well as reduces sensitivity to chemotherapy, leading to worse survival outcomes. Based on this association, the investigators also point to a possible therapeutic strategy for endometrial cancer (EC). The results were published recently in Endocrinology. The team, led by Peter...
