Researchers from the University of Basel and University Hospital Basel have identified how the sensory perception of a meal generates a signal to the pancreas to ramp up insulin production: inflammatory factor interleukin 1 beta (IL1β), which is also involved in the immune response to pathogens or in tissue damage. The team reported their findings...
A pancreatic cancer “time machine” has revealed that the disease is even more unpredictable than previously thought: Cancer cells promote each other’s invasiveness when they grow together, according to a paper recently published in Small. Researchers led by Stephen Konieczny, PhD, professor of biological sciences at Purdue University, and Bumsoo Han, PhD, professor of biomedical...
The country was saddened to learn over the weekend that Rep. John Lewis (D-Ga.), the legendary Civil Rights activist, was being treated for stage four pancreatic cancer. “While I am clear-eyed about the prognosis, doctors have told me that recent medical advances have made this type of cancer treatable in many cases, that treatment options...
High fasting glucose levels may increase the risk of pancreatic cancer, according to a study recently published in The Journal of Clinical Endocrinology & Metabolism. Researchers led by Cheol-Young Park, MD, PhD, of Kangbuk Samsung Hospital in Seoul, Korea, point out that a recent case-control study showed that patients diagnosed with pancreatic cancer had hyperglycemia...
Last month, our team presented data showing apolipoprotein C-III (apoC-III) inhibition with a RNA-targeted antisense therapy called volanesorsen effectively lowered triglycerides in patients with hypertriglyceridemia by 70%. This data was presented today at the National Lipid Association annual meeting in Philadelphia. Volanesorsen is designed to reduce the production of apoC-III, a protein produced in the...
If you haven’t heard of the JDRF Network for the Pancreatic Organ Donors with Diabetes aka nPOD, you will. nPOD is not just a research lab or a clearing house for pancreas tissue from donors with diabetes, it’s on the front lines to finding a cure. Last December, during the International Diabetes Federation World Diabetes...
A group of concerned patients and care providers for a rare disease have announced the formation of the first-ever organization dedicated to providing education and support for people living with familial chylomicronemia syndrome (FCS), a rare and potentially life-threatening genetic lipid disorder. The FCS Foundation will provide a range of educational materials and support services...
Once considered a “last resort” in patients with chronic pancreatitis, a new study shows that a total pancreatectomy with islet autotransplantation, sooner rather than later, can stave off the onset of diabetes and improve quality of life. A diagnosis of chronic pancreatitis (CP) once doomed a patient to significantly diminished quality of life (QOL) at...
If you haven’t heard of the JDRF Network for the Pancreatic Organ Donors with Diabetes aka nPOD, you will. nPOD is not just a research lab or a clearing house for pancreas tissue from donors with diabetes, it’s on the front lines to finding a cure. Last December, during the International Diabetes Federation World Diabetes...
