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Mighty Mouse: Could a Part of the Brain Unlock the Key to Combatting Obesity?

A new mouse study shows promise in addressing the ongoing worldwide obesity epidemic. By targeting a specific brain molecule, researchers could be on the path to a therapy that would potentially enable patients to reduce calories while increasing exercise levels. If Constantine A. Stratakis, MD, DSci, PhD, had his way, clinicians could soon offer their...
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Researchers Develop First-in-Class Humanized Antibody Targeting Bone and Fat

A treatment for obesity and osteoporosis could be on the horizon as Mount Sinai researchers have developed a first-in-class humanized antibody to the follicle-stimulating hormone (FSH) that will reduce body fat, increase bone mass, enhance metabolism, and lower cholesterol. The antibody has the potential to prevent and treat obesity, osteoporosis, and hypercholesterolemia — diseases that...
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Cause & Effect: Patients with Obesity and Thyroid Function Testing

According to a new guideline from the European Society of Endocrinology, patients with obesity should be routinely tested for thyroid function. However, testing for other endocrine-related conditions should be guided by the presence of symptoms. The endocrine system and obesity can have a push-pull relationship. Some endocrine disorders — such as hypothyroidism and Cushing’s syndrome...
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Eating a Late Dinner Linked to Weight Gain

Eating a late dinner may contribute to weight gain and high blood sugar, according to a small study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism. Over 2.1 billion adults are estimated to have overweight or obesity which make health complications like diabetes and high blood pressure more likely. Some studies suggest that consuming calories...
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People with Brown Fat May Burn 15 Percent More Calories

New data highlights how cold exposure activates brown fat, energy metabolism Short-term cold exposure may help people with brown fat burn 15 percent more calories than those without, according to a small study published in The Journal of Clinical Endocrinology & Metabolism. Unlike white fat, brown fat burns calories through fatty acid oxidation and heat production and is considered a promising target in the fight against the obesity epidemic. The biggest activator of brown fat is moderate cold exposure. “This data improves our understanding of how brown fat works...