Last month Corcept Therapuetics Incoporated announced that the U.S. Food and Drug Administration (FDA) filed its New Drug Application (NDA) submission for the company’s proprietary, selective cortisol modulator, relacorilant, to treat patients with endogenous hypercortisolism (Cushing’s syndrome). Corcept’s NDA is based on positive results from the pivotal GRACE trial and confirmatory evidence from the Phase 3 GRADIENT...
A recent study entitled “Association Between Per- and Polyfluoroalkyl Substance Exposures and Thyroid Homeostasis Parameters,” published in the Journal of Clinical Endocrinology & Metabolism, has found that exposure to per- and polyfluoroalkyl substances (PFAS) — a group of synthetic chemicals used in industrial and consumer products — may alter thyroid hormone sensitivity, potentially affecting metabolism...
The World Health Organization reports that obesity affects one in eight people globally, making it a major public issue. Yet obesity is not just about diet, exercise, and genes — something else must be afoot. Recently, evidence has pointed to an invisible but powerful culprit: dioxins and dioxin-like polychlorinated diphenyls (DL-PCBs), according to “Association Between...
It is well documented that endocrine-disrupting chemicals (EDCs) are virtually inescapable in everyday life since they are present in everything from food packaging and clothing to flame retardants toys. An upcoming ENDO 2025 session, “Thyroid Disruptors,” examines how EDCs affect thyroid function in pregnancy, childhood, and the link to an increased thyroid cancer risk in...
Doctor AI will see you now — eventually. A new study from The Journal of Clinical Endocrinology & Metabolism has demonstrated how artificial intelligence (AI) can enhance the accuracy of diagnosing Cushing’s syndrome (CS), a rare but serious endocrine disorder caused by excessive cortisol production. Cushing’s syndrome is characterized by a broad spectrum of symptoms,...
Andrea C. Gore, PhD, of the University of Texas in Austin, discusses her recent Journal of the Endocrine Society paper, which found that early-life exposure to a class of endocrine-disrupting chemicals called polychlorinated biphenyls – banned for decades but persistent in the environment — may lead to behavioral problems later in life. Late last year,...
Recently I was watching a couple of movies from the 1970s; one was a drama filmed in New York City and the other was a documentary filmed in California. There were plenty of random shots of people in streets as well as crowds at various events throughout both. However, one thing about both movies that...
A third generation of the latest cholesterol-lowering medication — PCSK9-inhibitors — will soon be available for patients with homozygous familial hypercholesterolemia (HoFH), according to a January 24 article in The Lancet Diabetes & Endocrinology. Affecting approximately 30,000 individuals worldwide, HoFH is a rare but serious genetic disorder in which patients have markedly elevated levels (>10...
As much as we know today about the endocrine system and the effects it has on the body, there remains so much that we do not know. Discoveries are made every day, and our understanding of the endocrine system is always growing and changing. Serving patients to the best of an endocrinologist’s abilities means being aware of all the latest developments in endocrine research. This includes the newest and most complete information concerning such endocrinology research topics as new treatments and new methods for disease prevention. Identifying symptoms and making the connections between those symptoms and endocrine disease can lead to greater understanding and ultimately better treatment for patients. More advanced prevention techniques can help patients stave off disease before it can impact their lives. Having the most current information can make a tremendous difference in the quality of life for your patients.
This section features some of the most current and forward-looking articles concerning the latest research in endocrinology. Written by and for endocrinologists, these articles are provided to keep you up to date with the most relevant developments in the field of endocrinology. You can access the information you need about new technology, new treatments and general information to help you serve your patients with better overall care. Our understanding of the endocrine system is always evolving. With Endocrine News, you can ensure that your knowledge of the field won’t be left behind. What’s more, your patients will always have access to the most advanced information out there.
Andrea C. Gore, PhD, of the University of Texas in Austin, discusses her recent Journal of the Endocrine Society paper, which found that early-life exposure to a class of endocrine-disrupting chemicals called polychlorinated biphenyls – banned for decades but persistent in the environment — may lead to behavioral problems later in life. Late last year,...
Recently I was watching a couple of movies from the 1970s; one was a drama filmed in New York City and the other was a documentary filmed in California. There were plenty of random shots of people in streets as well as crowds at various events throughout both. However, one thing about both movies that...
