The Phase 3 PANORAMA trial evaluating aflibercept injection in patients with moderately severe and severe non-proliferative diabetic retinopathy (NPDR) met its one-year (52-week) primary endpoint and key secondary endpoints, the drug’s manufacturer announced today. Regeneron Pharmaceuticals is marketing the drug as EYELA. On the primary endpoint at one year, 80% and 65% of patients receiving...
As new statistics reveal an alarming rate of obesity in the U.S., more and more people are opting for weight loss surgery to combat this disease. However, there are myriad side effects to be concerned about other than weight regain that range from addiction to possible suicide risk. Last month, the Centers for Disease Control...
Medicare’s decision to extend coverage to continuous glucose monitoring systems should expand use of the technology — and improve glucose control among seniors. New Medicare rules that extend reimbursement to include continuous glucose monitoring (CGM) systems are already leading to greater use among the senior population of a technology shown to improve glycemic control,...
Aside from the chances of becoming addicted or even dying from an overdose, opioids have also proven damaging to the endocrine system. An awareness by both patients and physicians is a much-needed first step to combatting these often severe conditions. Opioids have been grabbing headlines for the past couple of years. They’ve become an epidemic,...
Endocrine Society’s Clinical Practice Guideline offers diagnosis, treatment recommendations The Endocrine Society today issued a Clinical Practice Guideline that offers best practices for healthcare providers on how to promptly diagnose, treat, and manage patients with congenital adrenal hyperplasia (CAH), an inherited endocrine disorder, throughout their entire lives. The guideline, titled “Congenital Adrenal Hyperplasia Due to...
Getting the ACT Together: Tumor Database Improves Pediatric Care
The International Pediatric Adrenocortical Tumor Registry is a database for young patients afflicted with these rare tumors. The result has created more personalized and targeted care as well as benefited the patient’s families and their physicians. Last October, the Journal of Clinical Oncology published a paper that described the clinical features and outcomes in children with...Heir on the Side of Caution: How a Von Hippel-Lindau Patient Is Managing Her Health
In the two decades since Stacy Lloyd was diagnosed with Von Hippel-Lindau, much has changed in genetic research, treatment, and counseling methods. Despite a complicated healthcare system, new methods are evolving constantly to treat, diagnose, and maybe even prevent this rare and often debilitating genetic disorder. The morning of June 28, 1996, Stacy Lloyd –...
Positive top-line results this week were announced from the multinational, pivotal Phase 3 SONICS study evaluating levoketoconazole for the treatment of endogenous Cushing’s syndrome. Strongbridge Biopharma is marketing the drug as RECORLEV™ . The open-label, single-arm SONICS study achieved statistical significance of its pre-specified primary endpoint, with 30 percent of patients achieving normalization of mean urinary...
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