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Low Socioeconomic Status Raises Pregnant Women’s Risk of Exposure to Thyroid-Disrupting Chemicals

Exposure to some endocrine-disrupting chemicals (EDCs) that harm the thyroid gland has increased over the past 20 years among U.S. women of childbearing age and pregnant women, especially among those with lower social and economic status, according to a study presented at ENDO 2024. The researchers focused this study on women who may be particularly...
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TED Patients Report Maintained Improvement 2 Years After Teprotumumab Infusions

Most patients with thyroid eye disease treated with teprotumumab didn’t require additional treatments nearly two years later, according to industry-supported research being presented Sunday at ENDO 2024 in Boston, Mass., and published in the journal Thyroid. “Thyroid eye disease is a lifelong autoimmune disease that can worsen or flare, regardless of how it has been treated....
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People with Hypothyroidism and Type D Personality May be More Likely to Experience Poor Treatment Outcomes

New research published in The Journal of Clinical Endocrinology & Metabolism finds a high prevalence of type D personalities among people with hypothyroidism.  Hypothyroidism is a condition in which the thyroid gland does not produce enough thyroid hormones. Between 10-15% of people with treated hypothyroidism experience persistent symptoms despite achieving normal thyroid hormone levels, and...
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Teprotumumab Improves Proptosis in Thyroid Eye Disease

Teprotumumab significantly improved proptosis versus placebo in longstanding/low inflammation thyroid eye disease (TED) according to data from the first placebo-controlled trial of the drug that was recently published in The Journal of Clinical Endocrinology & Metabolism. (Horizon Therapeutics funded the trial and is marketing the drug as TEPEZZA.) Researchers led by Raymond S. Douglas, MD,...
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Standardized Testing: Universal Risk Stratification System Needed for Thyroid Nodules

With thyroid cancer patients often getting different — and sometimes conflicting — treatment recommendations from a variety of diagnostic tools, Priyanka Majety, MD, talks to Endocrine News about why it’s time for clinicians to coalesce around a single set of standards for these cases, which could potentially eliminate unnecessary procedures. Priyanka Majety, MD, assistant professor...
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Researchers Generate Functional Parathyroid Glands from Mouse Embryonic Stem Cells

Functional parathyroid glands (PTGs) can be generated from mouse embryonic stem cells (mESCs), according to a study published in Proceedings of the National Academy of Sciences (PNAS). Researchers in the Stem Cell Therapy Laboratory at Tokyo Medical and Dental University point out that treatment of hypoparathyroidism requires lifelong replacement therapy. Conventional management includes calcium supplements and...
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A Second Opinion

A novel approach to treating hypothyroidism shifts the focus from TSH levels. Rudolf Hoermann, MD, PhD, a consulting endocrinologist based in Australia, talks to Endocrine News about a new approach to treating patients with hypothyroidism. Hoermann counters that regulating the HPT axis from a T-3-inclusive perspective as well as considering other factors aside from TSH...

Endocrine News provides the latest news and research articles on thyroid conditions and treatment. For more info read this month’s issue of Endocrine News.