The Endocrine Society achieved a major victory in the new European Union (EU) Chemicals Strategy for Sustainability (CSS) by including several priority actions on endocrine-disrupting chemicals (EDCs) within the strategy. The CSS commits the EU towards a series of actions to better protect citizens and the environment and promote innovation in safe and sustainable chemicals....
When surgical treatment for three patients with pheochromocytoma was delayed due to COVID-19 restrictions, clinical endocrine fellow Emily A. Japp, MD, and team at the Icahn School of Medicine at Mount Sinai in New York City found a unique solution. Going beyond clinical guideline recommendations while closely monitoring the patients remotely resulted in a tailored...
Progression of Acromegalic Arthropathy Observed in Long-Term Study
Radiographic arthropathy progresses significantly in patients with long-term, well-controlled acromegaly, according to a study recently published in The Journal of Clinical Endocrinology & Metabolism. Researchers led by Iris C. M. Pelsma, MD, MSc, of Leiden University Medical Center in The Netherlands, point out that one of the long-term complications of acromegaly is acromegalic arthropathy, which...
Phase 3 Trial Data Shows Positive Results for Oral Treatment of Acromegaly
Data presented last month at ENDO 2021 from Phase 3 of the MPOWERED study showed that oral octreotide capsules improved clinical symptoms and other patient-reported outcomes compared to long-acting injectable somatostatin receptor ligands (iSRLs) in patients with acromegaly. In addition, oral octreotide capsules met the pre-specified non-inferiority margin compared to long-acting iSRLs in maintenance of...
Researchers Determine Best Predictors of Acromegaly Remission Following Transsphenoidal Surgery
Tumor size and random growth hormone concentration at diagnosis are the best predictors for remission of acromegaly after transsphenoidal surgery (TSS), according to a study recently published in The Journal of Clinical Endocrinology & Metabolism. Researchers led by Eva C. Coopmans, MD, of Erasmus University Medical Center in Rotterdam, The Netherlands, point out that TSS...
New Integrated Data Show Promise for Novel Thyroid Eye Disease Drug
New pooled data from Phase 2 and Phase 3 clinical trials further reinforce that teprotumumab-trbw significantly improves proptosis (eye bulging) and diplopia (double vision) for thyroid eye disease (TED) in patients in different subgroups, with most maintaining a long-term response. The results were published recently in The Lancet Diabetes & Endocrinology. Teprotumumab-trbw is a fully human...
Researchers Develop Machine-Learning Prediction Model to Improve Medical Management of Acromegaly
Machine learning (ML), a type of artificial intelligence, could be used to predict how patients with acromegaly respond to first-generation somatostatin receptor ligands (fg-SRLs), according a study recently published in The Journal of Clinical Endocrinology & Metabolism. Researchers led by Mônica Gadelha, MD, PhD, of the Endocrine Unit and Neuroendocrinology Research Center at the Medical...
Study Examines Body-Composition Changes with Long-Term Pegvisomant Therapy of Acromegaly
Long-term pegvisomant therapy for acromegaly can lead to a sustained increase in adiposity but no change in skeletal muscle mass, according to a study recently published in Journal of the Endocrine Society. Researchers led by Pamela U. Freda, MD, of the Columbia University Department of Medicine in New York, point out that pegvisomant, a growth...
As much as we know today about the endocrine system and the effects it has on the body, there remains so much that we do not know. Discoveries are made every day, and our understanding of the endocrine system is always growing and changing. Serving patients to the best of an endocrinologist’s abilities means being aware of all the latest developments in endocrine research. This includes the newest and most complete information concerning such endocrinology research topics as new treatments and new methods for disease prevention. Identifying symptoms and making the connections between those symptoms and endocrine disease can lead to greater understanding and ultimately better treatment for patients. More advanced prevention techniques can help patients stave off disease before it can impact their lives. Having the most current information can make a tremendous difference in the quality of life for your patients.
This section features some of the most current and forward-looking articles concerning the latest research in endocrinology. Written by and for endocrinologists, these articles are provided to keep you up to date with the most relevant developments in the field of endocrinology. You can access the information you need about new technology, new treatments and general information to help you serve your patients with better overall care. Our understanding of the endocrine system is always evolving. With Endocrine News, you can ensure that your knowledge of the field won’t be left behind. What’s more, your patients will always have access to the most advanced information out there.
