The U.S. Food and Drug Administration has approved romosozumab-aqqg to treat osteoporosis in postmenopausal women at high risk of breaking a bone (fracture). These are women with a history of osteoporotic fracture or multiple risk factors for fracture, or those who have failed or are intolerant to other osteoporosis therapies. The drug will be marketed...
Endocrine News talks with Clifford Rosen, MD, chair of the task force that created the latest Endocrine Society Clinical Practice Guideline on Pharmacological Management of Osteoporosis in Post-Menopausal Women. In March, the Endocrine Society issued a Clinical Practice Guideline on treating post-menopausal women with osteoporosis. Titled “Pharmacological Management of Osteoporosis in Post-Menopausal Women: An Endocrine...
A paper recently published in Endocrine Reviews covers atypical femur fractures (AFFs) and examines their relationship with bisphosphonates (BPs), as well as prevention and treatment of these rare but devastating bone breaks. The review, by Dennis M. Black, PhD, of the University of California, San Francisco, et al, points out that BPs have been the...
Children of parents who smoke have evidence of impaired bone health in adulthood, according to a study recently published in The Journal of Clinical Endocrinology and Metabolism. Researchers led by Markus Juonala, MD, PhD, of the University of Turku and Division of Medicine, Turku University Hospital, and FinlandMurdoch Childrens Research Institute in Parkville, Victoria, Australia,...
Study finds oral side effects are uncommon and manageable Oral complications are rare in women taking medications for postmenopausal osteoporosis, according to a study published in The Journal of Clinical Endocrinology & Metabolism. An oral complication called osteonecrosis of the jaw (ONJ) is exposed bone in the jaw that is slow to heal (8 weeks...
Patients with type 1 diabetes and poor blood sugar control face a higher risk of fragility fracture—any fall from standing height or less that results in a broken bone—than type 1 diabetes patients with good blood sugar control, according to a study published in The Journal of Clinical Endocrinology & Metabolism. “We investigated the association between...
Children born in the most recent century have bones that reach full maturity earlier – by nearly 10 months in girls and nearly seven months in boys, according to a study recently published in Clinical Orthopaedics and Related Research. Researchers led by Dana Duren, PhD, director of orthopaedic research at the Thompson Laboratory for Regenerative Orthopaedics...
Sundeep Khosla, MD, talks to Endocrine News about his ENDO 2019 plenary talk on treating osteoporosis via cellular senescence with the ultimate goal of making the golden years truly golden with a better quality of life. ENDO 2019 is now about 10 weeks away, and while we’re excited about all the sights, sounds, and smells...
Endocrine News talks with Clifford Rosen, MD, chair of the task force that created the latest Endocrine Society Clinical Practice Guideline on Pharmacological Management of Osteoporosis in Post-Menopausal Women. In March, the Endocrine Society issued a Clinical Practice Guideline on treating post-menopausal women with osteoporosis. Titled “Pharmacological Management of Osteoporosis in Post-Menopausal Women: An Endocrine...
Sundeep Khosla, MD, talks to Endocrine News about his ENDO 2019 plenary talk on treating osteoporosis via cellular senescence with the ultimate goal of making the golden years truly golden with a better quality of life. ENDO 2019 is now about 10 weeks away, and while we’re excited about all the sights, sounds, and smells...
