The pharmacology data focus on the human body’s homeostatic response to potent HSD-1 inhibition by SPI-62. Results highlight that urinary free cortisol is distinct from intracellular cortisol that causes symptoms in patients with Cushing’s syndrome or autonomous cortisol secretion. Sparrow Pharmaceuticals, a clinical-stage biopharmaceutical company developing novel, targeted therapies to address unmet needs in both endocrinology...
When the ENDO 2022 session “Clinical Year in Review: All Things Adrenal” gets underway, Gary Hammer, MD, PhD, will treat attendees to the series of advances that have been made in adrenal science and clinical practice over the last two years, from adrenal homeostasis, glucocorticoid biology, and adrenal insufficiency to Cushing’s, tumors, pheochromocytoma, and more.... A new study finds that even low levels of the “mild cortisol excess” associated with adrenal incidentalomas can increase cardiometabolic risk. Benign tumors on adrenal glands may not be so benign when it comes to patients’ overall health, according to the largest study to date on the topic. An international consortium of researchers found...
The discovery of a new mutation could eventually hold the key to treating patients with adrenal carcinoma. Endocrine News talks with Emilia Pinto, PhD, a St. Jude’s Children’s Research Hospital scientist, who hopes that this new finding will raise awareness around the world in families who might be at a greater risk for this rare...
Patients with classic congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency (21OHD) may benefit from the drug tildacerfont, according to the results from two Phase 2 clinical studies recently published in The Journal of Clinical Endocrinology & Metabolism. Researchers led by Chris N. Barnes, PhD, of Spruce Biosciences (who funded the trial), point out that...
Since the first, all-virtual ENDO 2021 stemmed from the lingering effects of the COVID-19 pandemic, Endocrine News presents an overview of the research that specifically addressed how the virus affects patients with common comorbidities. These studies looked at COVID-19’s effects on patients with obesity, hyperglycemia, adrenal insufficiency, and a lack of vitamin D, and provide... When surgical treatment for three patients with pheochromocytoma was delayed due to COVID-19 restrictions, clinical endocrine fellow Emily A. Japp, MD, and team at the Icahn School of Medicine at Mount Sinai in New York City found a unique solution. Going beyond clinical guideline recommendations while closely monitoring the patients remotely resulted in a tailored...
Heart disease and infections rank as top causes of death among those with rare disorder Endogenous Cushing’s syndrome, a rare hormonal disorder, is associated with a threefold increase in death, primarily due to cardiovascular disease and infection, according to a study presented at ENDO 2021. The research, according to the study authors, is the largest...
Adrenal Disorders And Adrenal Cancer Information
Though rare, affecting around 200 people per year, adrenal cancer is no less devastating when a family faces a diagnosis. Because it’s so rare, getting access to the right information and treatment is challenging. It’s not uncommon for a patient with this diagnosis to find that his or her doctor has never faced adrenal cancer before. For that reason, a trusted resource for accurate and timely information is critical to the modern endocrinology practice.
In addition, benign adrenal tumors, which affect one out of every 10 people who have an imaging test done of the adrenal gland, can have serious health effects. To help doctors and patients understand adrenal diseases, including tumors and cancers, Endocrine News has collected a number of recent and relevant articles on the topic on this page. For the information you need about adrenal disease, bookmark this page and refer to it on a regular basis.
Clinical Trials and Recent Research Studies
For doctors to make informed decisions for their patients about adrenal disorders, they need accurate information about the most recent research studies and clinical trials. Sometimes, accessing that information is not easy, especially for rare disorders and diseases. Endocrine News brings all of that research into one place, providing the data you need to make the right decisions for your practice and your patients.
Providing Hope for Adrenal Cancer Patients
For patients who have been diagnosed with adrenal cancer, this page will provide a measure of hope by offering insight into adrenal cancer treatments. Since only about 200 patients are diagnosed with this particular disease each year, endocrinologists are often unprepared to treat it. Here, however, doctors and patients can find information about what treatment options are available. Research about new, promising treatments will also be posted here as it comes available, providing hope to patients and doctors alike.
