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Investigators Describe Changes to Pancreatic Beta-Cell at Onset of Type 1 Diabetes

New research by investigators at Joslin Diabetes Center sheds new light on the specific changes β-cells go through at the onset of type 1 diabetes. Their findings—published in Nature Cell Biology—offer new avenues for targeted interventions for the chronic autoimmune condition.  “In the field of type 1 diabetes, research has largely focused on understanding the immune...
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Eureka 2023! Part IV: Top Endocrine Discoveries

For the ninth year running, Endocrine News talks to editors from Endocrine Society publications to unearth the endocrine nuggets of 2023. Here, the editors of The Journal of Clinical Endocrinology & Metabolism and JCEM Case Reports weigh in on what they think qualify as the year’s biggest discoveries in endocrine science. Editor-in-Chief of JCEM, Paul...
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Eureka 2023! Part III: Top Endocrine Discoveries

For the ninth year running, Endocrine News talks to editors from Endocrine Society publications to unearth the endocrine nuggets of 2023. Here, the editors of the Journal of the Endocrine Society weigh in on what they think qualify as the year’s biggest discoveries in endocrine science. For JES Editor-in-Chief Zeynep Madak-Erdogen, PhD, associate professor of...
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Eureka 2023! Part II: Top Endocrine Discoveries

For the ninth year running, Endocrine News talks to editors from Endocrine Society publications to unearth the endocrine nuggets of 2023. Here, the editors of Endocrinology weigh in on what they think qualify as the year’s biggest discoveries in endocrine science. Endocrinology Editor-in-Chief Carol A. Lange, PhD, professor of medicine (Division of Hematology, Oncology, and...
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Eureka 2023! Part I: Top Endocrine Discoveries

For the ninth year running, Endocrine News talks to editors from Endocrine Society publications to unearth the endocrine nuggets of 2023. Here, the editors of the Endocrine Reviews weigh in on what they think qualify as the year’s biggest discoveries in endocrine science. The endocrine Gold Rush of ’22 from last year’s issue might have...
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Researchers Observe Beta-Arrestin’s Mechanism in GPCRs

Beta-arrestins attach themselves to outer cell membranes, waiting for hormones or neurotransmitters to land on receptors – an unexpected and surprising finding recently published in Cell. Researchers led by Davide Calebiro, MD, professor of Molecular Endocrinology in the Institute of Metabolism and Systems Research at the University of Birmingham and Co-Director of the Centre of...
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Mouse Study Hints at Specific Brain Receptor behind PCOS Symptoms

Deletion of androgen receptors (ARs) in leptin receptor (LepRb) neurons improves estrous cycles, providing a possible therapeutic target for the symptoms of polycystic ovarian syndrome (PCOS), according to a mouse study recently published in Endocrinology. Researchers led by Carol F. Elias, PhD, of the University of Michigan Medical School’s Department of Molecular and Integrative Physiology,...