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Autocrine Prolactin Associated with Endometrial Cancer Growth, Metastasis, Reduced Sensitivity to Chemotherapy

Researchers have shown that autocrine human prolactin (hPRL) promotes endometrial tumor growth and metastasis, as well as reduces sensitivity to chemotherapy, leading to worse survival outcomes. Based on this association, the investigators also point to a possible therapeutic strategy for endometrial cancer (EC). The results were published recently in Endocrinology. The team, led by Peter...
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Researchers Studying Novel Gestational Diabetes Screening Alternative

Researchers at Brigham and Women’s Hospital (BWH) recently published a study demonstrating the potential clinical utility of glycated CD59 (GCD59) as a novel biomarker for the screening and diagnosis of gestational diabetes mellitus (GDM). The data from this study showed that a single blood test that measures plasma GCD59 at week 24-28 of gestation identified...
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Case of the Month: Endocrine Board Review Online

endocrine review board This issue highlights Endocrine Board Review Online. Test your clinical knowledge and prepare for your exam with access to live course session recordings and case questions. Available on the online store.   Clinical Vignette A 50-year-old woman presents to your office with concerns of hirsutism and male-pattern balding. She had normal menarche at age 12...
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Case of the Month: New ESAP Edition

esap 2017 cover This case highlights newest edition of Endocrine Self-Assessment Program (ESAP), which is also available as a bundle with our special edition ESAP. Available on the online store. Clinical Vignette A 32-year-old woman with panhypopituitarism recently moved to your city and sees you in consultation for her ongoing care. At age 12 years a craniopharyngioma was...
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Can Childhood Obesity be Prevented Before Conception?

First-ever exercise, nutrition program will seek answers by focusing on Cleveland mothers A Case Western Reserve University School of Medicine and MetroHealth System researcher, along with Cleveland Clinic’s director of metabolic research, have received federal funding to determine if childhood obesity can be prevented before women become pregnant. The first-ever Cleveland-based study will explore whether...
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Women Dissatisfied with Long PCOS Diagnosis Process

A large international survey of women with polycystic ovary syndrome (PCOS) found nearly two in three were dissatisfied with the length of time they waited and the number of healthcare professionals they had to see before they received a diagnosis, according to a new study published The Journal of Clinical Endocrinology & Metabolism. Researchers led...