New research published in The Journal of Clinical Endocrinology & Metabolism finds a high prevalence of type D personalities among people with hypothyroidism. Hypothyroidism is a condition in which the thyroid gland does not produce enough thyroid hormones. Between 10-15% of people with treated hypothyroidism experience persistent symptoms despite achieving normal thyroid hormone levels, and...
Teprotumumab significantly improved proptosis versus placebo in longstanding/low inflammation thyroid eye disease (TED) according to data from the first placebo-controlled trial of the drug that was recently published in The Journal of Clinical Endocrinology & Metabolism. (Horizon Therapeutics funded the trial and is marketing the drug as TEPEZZA.) Researchers led by Raymond S. Douglas, MD,...
For Your Information: Recent Revelations on Thyroid Cancer Treatment
Thyroid cancer is the most common endocrine cancer in the world with over 62,000 newly diagnosed cases each year in the U.S. alone. Here, we look at some of the latest research that includes a study from Endocrine Reviews on radiation-induced thyroid cancer; a JCEM Case Reports paper on false positive results in metastatic thyroid...
Standardized Testing: Universal Risk Stratification System Needed for Thyroid Nodules
With thyroid cancer patients often getting different — and sometimes conflicting — treatment recommendations from a variety of diagnostic tools, Priyanka Majety, MD, talks to Endocrine News about why it’s time for clinicians to coalesce around a single set of standards for these cases, which could potentially eliminate unnecessary procedures. Priyanka Majety, MD, assistant professor...
Researchers Generate Functional Parathyroid Glands from Mouse Embryonic Stem Cells
Functional parathyroid glands (PTGs) can be generated from mouse embryonic stem cells (mESCs), according to a study published in Proceedings of the National Academy of Sciences (PNAS). Researchers in the Stem Cell Therapy Laboratory at Tokyo Medical and Dental University point out that treatment of hypoparathyroidism requires lifelong replacement therapy. Conventional management includes calcium supplements and...
A novel approach to treating hypothyroidism shifts the focus from TSH levels. Rudolf Hoermann, MD, PhD, a consulting endocrinologist based in Australia, talks to Endocrine News about a new approach to treating patients with hypothyroidism. Hoermann counters that regulating the HPT axis from a T-3-inclusive perspective as well as considering other factors aside from TSH...
Solving the Hypothyroidism Puzzle: Q&A: Antonio Bianco, MD, PhD
Two months after his new book, Rethinking Hypothyroidism, hit the shelves, Antonio Bianco, MD, PhD, talks to Endocrine News about, well, rethinking hypothyroidism. From his research of thyroid metabolism and deiodinases to why researchers and clinicians have often been so mystified by hypothyroidism for centuries, Bianco discusses why treating hypothyroidism is a “solution followed by...Pro Golfer Azahara Muñoz Shares Her Experience with Hashimoto’s Disease
When professional golfer Azahara Muñoz started developing symptoms of Hashimoto’s thyroiditis – tiredness, cold extremities – she chalked them up to practicing too hard or traveling too much. It’s a stressful job. “You almost always have an excuse for it,” she says. But then around 2016, Muñoz noticed she began suffering from anxiety. Her hair...Endocrine News provides the latest news and research articles on thyroid conditions and treatment. For more info read this month’s issue of Endocrine News.
